Species

KNApSAcK Entry

Organism name Lysimachia spp.
Genus Lysimachia
Family Myrsinaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lysimachia
Linked NCBI taxonomy ID 59977
Linked level genus

Family

Family in NCBI taxonomy Primulaceae
ID 4335

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005538 External link 512 Isorhamnetin 3-robinobioside
/ Isorhamnetin 3-O-robinobioside
CHEMBL84174
CHEMBL258394
CHEMBL1711509
CHEMBL2165403
7 / 1 / 2 No. 1 No. 15
C00005730 External link 512 Myricitrin
/ Myricetin 3-O-rhamnoside
/ Myricetin 3-O-alpha-L-rhamnoside
/ Myricetin 3-O-alpha-L-rhamnopyranoside
CHEMBL454576
CHEMBL522983
CHEMBL1599224
C008577
25 / 11 / 11 No. 2 No. 15

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P07237 Protein disulfide-isomerase Enzyme C00005538 C00005730 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005538 C00005730 0 / 0
P03372 Estrogen receptor NR3A1 C00005538 1 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00005730 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00005730 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00005730 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005730 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00005730 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005730 0 / 0
O75496 Geminin Unclassified protein C00005538 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00005538 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005730 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005730 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00005730 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005538 0 / 0
P06746 DNA polymerase beta Enzyme C00005730 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005538 0 / 1
Q99700 Ataxin-2 Unclassified protein C00005730 1 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00005730 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005730 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00005730 4 / 3
P34949 Mannose-6-phosphate isomerase Enzyme C00005730 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00005730 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005730 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00005730 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00005730 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00005730 1 / 1
Q13951 Core-binding factor subunit beta Unclassified protein C00005730 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00005730 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005730 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#602579 Congenital disorder of glycosylation, type ib; cdg1b P34949
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (13)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00118 Congenital disorders of glycosylation (CDG) type I P34949 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)