| Organism name | Asarum maximum | 
|---|---|
| Genus | Asarum | 
| Family | Aristolochiaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Asarum maximum | 
|---|---|
| Linked NCBI taxonomy ID | 647436 | 
| Linked level | species | 
| Family in NCBI taxonomy | Aristolochiaceae | 
|---|---|
| ID | 16727 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | Magnoliophyta | 
|---|---|
| ID | 3398 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | 
                        # of proteins in
                         ChEMBL interaction / related OMIM / related KEGG DISEASE  | 
                      
                        # of genes in
                         CTD interaction / related diseases  | 
                      
                        KCF-S
                         cluster  | 
                      
                        phytochemical
                         cluster  | 
                      figure | 
|---|---|---|---|---|---|---|---|---|
| 
                        C00000601
                        
                           | 
                      
                        (+)-Sesamin
                         | 
                      
                        CHEMBL43469
                         CHEMBL252915 CHEMBL1572261 CHEMBL1591714 CHEMBL1708854 CHEMBL1904496 CHEMBL1968861  | 
                      
                        C054125
                         | 
                      20 / 24 / 15 | 0 / 5 | No. 621 | No. 21 | 
                         
                       | 
                    
| accession | description | class description | KNApSAcK metabolite in interactions | 
                          # of diseases
                           (OMIM / KEGG)  | 
                      
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000601 | 1 / 0 | 
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000601 | 4 / 1 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000601 | 0 / 1 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00000601 | 2 / 3 | 
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00000601 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000601 | 2 / 0 | 
| O75496 | Geminin | Unclassified protein | C00000601 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000601 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000601 | 7 / 3 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000601 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000601 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000601 | 0 / 0 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000601 | 2 / 2 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000601 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000601 | 1 / 1 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000601 | 0 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000601 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000601 | 4 / 3 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000601 | 0 / 0 | 
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00000601 | 1 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | 
                            P63092
                             | 
                        
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 | 
                            Q13148
                             | 
                        
| #114500 | Colorectal cancer; crc | 
                            P84022
                             | 
                        
| #119900 | Digital clubbing, isolated congenital | 
                            P15428
                             | 
                        
| #609535 | Drug metabolism, poor, cyp2c19-related | 
                            P33261
                             | 
                        
| #608902 | Drug metabolism, poor, cyp2d6-related | 
                            P10635
                             | 
                        
| #600274 | Frontotemporal dementia; ftd | 
                            P10636
                             | 
                        
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | 
                            P15428
                             | 
                        
| #613795 | Loeys-dietz syndrome, type 3; lds3 | 
                            P84022
                             | 
                        
| #174800 | Mccune-albright syndrome; mas | 
                            P63092
                             | 
                        
| #607948 | Mycobacterium tuberculosis, susceptibility to | 
                            P11473
                             | 
                        
| #166350 | Osseous heteroplasia, progressive; poh | 
                            P63092
                             | 
                        
| #260540 | Parkinson-dementia syndrome | 
                            P10636
                             | 
                        
| #172700 | Pick disease of brain | 
                            P10636
                             | 
                        
| #102200 | Pituitary adenoma, growth hormone-secreting | 
                            P63092
                             | 
                        
| #103580 | Pseudohypoparathyroidism, type ia; php1a | 
                            P63092
                             | 
                        
| #603233 | Pseudohypoparathyroidism, type ib; php1b | 
                            P63092
                             | 
                        
| #612462 | Pseudohypoparathyroidism, type ic; php1c | 
                            P63092
                             | 
                        
| #253300 | Spinal muscular atrophy, type i; sma1 | 
                            Q16637
                             | 
                        
| #253550 | Spinal muscular atrophy, type ii; sma2 | 
                            Q16637
                             | 
                        
| #253400 | Spinal muscular atrophy, type iii; sma3 | 
                            Q16637
                             | 
                        
| #271150 | Spinal muscular atrophy, type iv; sma4 | 
                            Q16637
                             | 
                        
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | 
                            P10636
                             | 
                        
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | 
                            P11473
                             | 
                        
| KEGG | name | UniProt | 
|---|---|---|
| H00036 | Osteosarcoma | 
                            P08684
                            (marker)
                             | 
                        
| H00058 | Amyotrophic lateral sclerosis (ALS) | 
                            P10636
                            (related)
                             Q13148 (related)  | 
                        
| H00077 | Progressive supranuclear palsy (PSP) | 
                            P10636
                            (related)
                             | 
                        
| H00078 | Frontotemporal lobar degeneration (FTLD) | 
                            P10636
                            (related)
                             | 
                        
| H00342 | Tuberculosis | 
                            P11473
                            (related)
                             | 
                        
| H00784 | Localized autosomal recessive hypotrichosis | 
                            P11473
                            (related)
                             | 
                        
| H01143 | Vitamin D-dependent rickets | 
                            P11473
                            (related)
                             | 
                        
| H01205 | Coumarin resistance | 
                            P11712
                            (related)
                             | 
                        
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | 
                            P15428
                            (related)
                             | 
                        
| H01246 | Isolated congenital nail clubbing (ICNC) | 
                            P15428
                            (related)
                             | 
                        
| H01171 | Poor drug metabolism (PM) | 
                            P33261
                            (related)
                             | 
                        
| H00244 | Pseudohypoparathyroidism | 
                            P63092
                            (related)
                             | 
                        
| H00441 | Progressive osseous heteroplasia (POH) | 
                            P63092
                            (related)
                             | 
                        
| H00501 | Fibrous dysplasia, polyostotic | 
                            P63092
                            (related)
                             | 
                        
| H00455 | Spinal muscular atrophy (SMA) | 
                            Q16637
                            (related)
                             |