PCIDB

Pithecellobium unguis-cati

Species

KNApSAcK Entry

Organism name Pithecellobium unguis-cati
Genus Pithecellobium
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Pithecellobium unguis-cati
Linked NCBI taxonomy ID 519515
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00006927 External link 512 Isoliquiritigenin 2'-methy ether
/ 4,4'-Dihydroxy-2'-methoxychalcone
CHEMBL253777
7 / 20 / 19 No. 92 No. 13

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily C00006927 9 / 3
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00006927 1 / 8
P12931 Proto-oncogene tyrosine-protein kinase Src Src C00006927 0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr C00006927 1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily C00006927 2 / 3
P11362 Fibroblast growth factor receptor 1 Fgfr C00006927 4 / 5
P10721 Mast/stem cell growth factor receptor Kit Pdgfr C00006927 4 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#101200 Apert syndrome P21802
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#123500 Crouzon syndrome P21802
#606764 Gastrointestinal stromal tumor; gist P10721
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#123150 Jackson-weiss syndrome; jws P21802
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
#601626 Leukemia, acute myeloid; aml P10721
#211980 Lung cancer P00533
#166250 Osteoglophonic dysplasia; ogd P11362
#101600 Pfeiffer syndrome P11362
P21802
#172800 Piebald trait; pbt P10721
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#273300 Testicular germ cell tumor; tgct P10721
#190440 Trigonocephaly 1; trigno1 P11362

KEGG DISEASE (19)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
P08581 (related)
P21802 (related)
H00022 Bladder cancer P00533 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)