Species

KNApSAcK Entry

Organism name Arthrobacter protophormiae
Genus Arthrobacter
Family Micrococcaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Arthrobacter protophormiae
Linked NCBI taxonomy ID 37930
Linked level species

Family

Family in NCBI taxonomy Micrococcaceae
ID 1268

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007568 External link 512 3-Hydroxyanthranilic acid
CHEMBL445304
D015095
9 / 2 / 2 0 / 2 No. 2138
C00007557 External link 512 o-Hydroxylaminobenzoate
No. 2192
C00007382 External link 512 Anthranilic acid
CHEMBL14173
C031385
6 / 4 / 4 6 / 4 No. 2192

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00007382 C00007568 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00007568 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00007382 1 / 1
Q96RI1 Bile acid receptor NR1H4 C00007382 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00007382 3 / 3
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00007382 0 / 0
Q15118 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial Pdhk C00007568 0 / 0
P11413 Glucose-6-phosphate 1-dehydrogenase Enzyme C00007568 1 / 2
O75164 Lysine-specific demethylase 4A Enzyme C00007568 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00007382 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00007568 0 / 0
P10747 T-cell-specific surface glycoprotein CD28 Unclassified protein C00007568 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00007568 1 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00007568 0 / 0

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00007382
3458 IFNG, IFG, IFI interferon, gamma C00007382
3592 IL12A, CLMF, IL-12A, NFSK, NKSF1, P35 interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) C00007382
3593 IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) C00007382
3606 IL18, IGIF, IL-18, IL-1g, IL1F4 interleukin 18 (interferon-gamma-inducing factor) C00007382
5604 MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1 mitogen-activated protein kinase kinase 1 (EC:2.7.12.2) C00007382

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300908 Anemia, nonspherocytic hemolytic, due to g6pd deficiency P11413
#613163 Gaba-transaminase deficiency P80404
#137800 Glioma susceptibility 1; glm1 O75874
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714

KEGG DISEASE (6)

KEGG name UniProt
H00101 Other phagocyte defects P11413 (related)
H00668 Anemia due to disorders of glutathione metabolism P11413 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D010024 Osteoporosis C00007382
C00007568
D019970 Cocaine-Related Disorders C00007382
D008114 Liver Neoplasms, Experimental C00007382
D011297 Prenatal Exposure Delayed Effects C00007382
D012509 Sarcoma C00007568