Species

KNApSAcK Entry

Organism name Cyperus capitatus
Genus Cyperus
Family Cyperaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cyperus capitatus
Linked NCBI taxonomy ID 529428
Linked level species

Family

Family in NCBI taxonomy Cyperaceae
ID 4609

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008026 External link 512 Sulfuretin
/ Sulphuretin
/ 6,3',4'-Trihydroxyaurone
CHEMBL490355
CHEMBL513487
C054989
42 / 37 / 34 No. 450 No. 13
C00008032 External link 512 6,3',4'-Trihydroxy-4-methoxy-5-methylaurone
No. 450 No. 13
C00014653 External link 512 4,6,3',4'-Tetrahydroxy-5-methylaurone
No. 450 No. 13
C00014656 External link 512 6,3'-Dihydroxy-4,4'-dimethoxy-5-methylaurone
No. 450 No. 13
C00014655 External link 512 6,3',4'-Trihydroxy-4-methoxy-7-methylaurone
No. 450 No. 13
C00014654 External link 512 4,6,3',4'-Tetrahydroxy-7-methylaurone
No. 450 No. 13
C00014657 External link 512 Rengasin trimethyl ether
/ 4,6,3',4'-Tetramethoxyaurone
CHEMBL1801772
No. 3237

Human Protein / Gene in interactions

42 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00008026 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00008026 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00008026 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00008026 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00008026 3 / 1
Q9HBX9 Relaxin receptor 1 Relaxin receptor C00008026 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00008026 1 / 0
P11473 Vitamin D3 receptor NR1I1 C00008026 2 / 3
P47901 Vasopressin V1b receptor Vasopressin and oxytocin receptor C00008026 0 / 0
P39748 Flap endonuclease 1 Enzyme C00008026 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00008026 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00008026 2 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00008026 4 / 2
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00008026 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00008026 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00008026 1 / 1
P09923 Intestinal-type alkaline phosphatase Enzyme C00008026 0 / 0
P05186 Alkaline phosphatase, tissue-nonspecific isozyme Enzyme C00008026 3 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00008026 1 / 2
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00008026 1 / 2
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00008026 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00008026 0 / 0
P10696 Alkaline phosphatase, placental-like Enzyme C00008026 0 / 1
P08253 72 kDa type IV collagenase M10A C00008026 1 / 3
O15118 Niemann-Pick C1 protein Unclassified protein C00008026 1 / 1
Q8WXD0 Relaxin receptor 2 Relaxin receptor C00008026 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00008026 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00008026 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00008026 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00008026 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00008026 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00008026 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00008026 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00008026 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00008026 0 / 0
O00487 26S proteasome non-ATPase regulatory subunit 14 Enzyme C00008026 0 / 0
O00255 Menin Unclassified protein C00008026 2 / 5
Q13951 Core-binding factor subunit beta Unclassified protein C00008026 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00008026 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00008026 0 / 0
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00008026 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00008026 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (37)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#114500 Colorectal cancer; crc P84022
Q14191
#219050 Cryptorchidism, unilateral or bilateral Q8WXD0
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#146300 Hypophosphatasia, adult P05186
#241510 Hypophosphatasia, childhood P05186
#241500 Hypophosphatasia, infantile P05186
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257220 Niemann-pick disease, type c1; npc1 O15118
#166350 Osseous heteroplasia, progressive; poh P63092
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (34)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00213 Hypophosphatasia P05186 (related)
H00025 Penile cancer P08253 (related)
H00028 Choriocarcinoma P08253 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00023 Testicular cancer P10696 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00609 46,XY disorders of sex development (Other) Q8WXD0 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)