Species

KNApSAcK Entry

Organism name Crotalaria prostrata
Genus Crotalaria
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Crotalaria prostrata
Linked NCBI taxonomy ID 1208119
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008714 External link 512 Taxifolin 3-galactosyl-(1->6)-glucoside
No. 48 No. 14
C00014428 External link 512 Crotaoprostrin
/ 2'-Hydroxy-3,4,5-methoxychalcone
CHEMBL521653
16 / 23 / 18 No. 79
C00014342 External link 512 4'-O-Methylcarthamidin 7-(2-p-coumaroylglucoside)
/ 5,6,7-Trihydroxy-4'-methoxyflavanone 7-(2-p-coumaroylglucoside)
No. 540

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00014428 0 / 0
P02545 Prelamin-A/C Unclassified protein C00014428 11 / 10
P11473 Vitamin D3 receptor NR1I1 C00014428 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00014428 0 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00014428 2 / 2
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00014428 2 / 0
O75496 Geminin Unclassified protein C00014428 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00014428 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00014428 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00014428 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00014428 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00014428 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00014428 4 / 3
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00014428 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00014428 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00014428 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (18)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)