Species

KNApSAcK Entry

Organism name Streptomyces sp. OH-1049
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009384 External link 512 3'-Hydroxydaidzein
/ 7,3',4'-Trihydroxyisoflavone
CHEMBL13486
C061213
4 / 7 / 4 8 / 0 No. 71 No. 15
C00009852 External link 512 NSC 678112
/ 8-Hydroxydaidzein
/ 7,8,4'-Trihydroxyisoflavone
CHEMBL242739
C061214
1 / 1 / 1 No. 71 No. 15
C00017701 External link 512 8-Chloro-3',4',5,7-tetrahydroxyisoflavone
C061216
No. 71 No. 15

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00009384 C00009852 1 / 1
P14174 Macrophage migration inhibitory factor Enzyme C00009384 1 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00009384 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00009384 5 / 3

8 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00009384
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00009384
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00009384
581 BAX, BCL2L4 BCL2-associated X protein C00009384
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00009384
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00009384
847 CAT catalase (EC:1.11.1.6) C00009384
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00009384

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231
#604302 Rheumatoid arthritis, systemic juvenile P14174
#278300 Xanthinuria, type i P47989

KEGG DISEASE (4)

KEGG name UniProt
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00192 Xanthinuria P47989 (related)