| Organism name | Streptomyces hygroscopicus DS 9751 (NRRL 3418) |
|---|---|
| Genus | Streptomyces |
| Family | Streptomycetaceae |
| Kingdom | Bacteria |
| Linked NCBI taxonomy name | Streptomyces |
|---|---|
| Linked NCBI taxonomy ID | 1883 |
| Linked level | genus |
| Family in NCBI taxonomy | Streptomycetaceae |
|---|---|
| ID | 2062 |
| Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
|---|---|
| ID | 2 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00017954
|
18631RP
/ RP 18631 / NSC 227186 / Clorobiocin / Chlorobiocin / Antibiotic 2562A |
CHEMBL303984
CHEMBL1172192 |
C006260
|
23 / 20 / 14 | No. 3473 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00017954 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00017954 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00017954 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00017954 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00017954 | 2 / 2 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00017954 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00017954 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00017954 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00017954 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00017954 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00017954 | 1 / 1 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00017954 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00017954 | 0 / 0 |
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00017954 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00017954 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00017954 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00017954 | 4 / 3 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00017954 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00017954 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00017954 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00017954 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00017954 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00017954 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|