Species

KNApSAcK Entry

Organism name Streptomyces tanashiensis MD706-Y4
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00017972 External link 512 Phosphoramidon
CHEMBL418012
CHEMBL41289
CHEMBL479579
CHEMBL563250
CHEMBL1318812
CHEMBL1742968
C008890
7 / 7 / 4 6 / 5 No. 5720

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein C00017972 2 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00017972 0 / 0
P42892 Endothelin-converting enzyme 1 M13 C00017972 1 / 0
P39748 Flap endonuclease 1 Enzyme C00017972 0 / 0
P12821 Angiotensin-converting enzyme M2 C00017972 4 / 2
P08473 Neprilysin M13 C00017972 0 / 2
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00017972 0 / 0

6 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00017972
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00017972
3792 KEL, CD238, ECE3 Kell blood group, metallo-endopeptidase (EC:3.4.24.-) C00017972
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00017972
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00017972
4922 NTS, NMN-125, NN, NT, NT/N, NTS1 neurotensin C00017972

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#613870 Hirschsprung disease, cardiac defects, and autonomic dysfunction P42892
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#267430 Renal tubular dysgenesis; rtd P12821
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601367 Stroke, ischemic P12821

KEGG DISEASE (4)

KEGG name UniProt
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) P08473 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) P08473 (marker)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D004487 Edema C00017972
D006973 Hypertension C00017972
D013272 Stomach Diseases C00017972
D013276 Stomach Ulcer C00017972
D013375 Substance Withdrawal Syndrome C00017972