Ochrolechia parella
Species
KNApSAcK Entry
| Organism name | Ochrolechia parella |
|---|---|
| Genus | |
| Family | |
| Kingdom |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Ochrolechia parella |
|---|---|
| Linked NCBI taxonomy ID | 129506 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Ochrolechiaceae |
|---|---|
| ID | 394531 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00039931
|
Parellin
|
No. 1342 |
|
|||||
|
C00030200
|
Ergosterol peroxide
/ Ergosterol 5,8-peroxide / (-)-Ergosterol 5,8-peroxide / 5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol / (-)-5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol |
CHEMBL434750
CHEMBL515808 CHEMBL1801968 CHEMBL1969254 |
C036071
|
1 / 0 / 0 | 1 / 4 | No. 2300 |
|
|
|
C00040630
|
Variolaric acid
|
CHEMBL220486
|
No. 2735 |
|
||||
|
C00036782
|
Parmelin
/ Atranorin / Usnarin acid |
CHEMBL173395
|
C026304
|
2 / 0 / 1 | 5 / 3 | No. 3861 |
|
|
|
C00017999
|
NSC 249981
/ Lecanoric acid |
CHEMBL1451874
|
C008263
|
10 / 8 / 13 | No. 3983 |
|
||
|
C00038413
|
alpha-Alectoronic acid
|
CHEMBL426543
|
No. 6909 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00017999 C00036782 | 0 / 1 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00017999 | 2 / 2 |
| O75496 | Geminin | Unclassified protein | C00017999 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00030200 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00017999 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00017999 | 3 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00017999 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00017999 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00036782 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00017999 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00017999 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00017999 | 1 / 2 |
5 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00030200
C00036782
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00036782
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00036782
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00036782
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00036782
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|