Species

KNApSAcK Entry

Organism name Penicillium notatum
Genus Penicillium
Family Trichocomaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Penicillium chrysogenum
Linked NCBI taxonomy ID 5076
Linked level species

Family

Family in NCBI taxonomy Aspergillaceae
ID 1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00023763 External link 512 Pyrocalciferol
CHEMBL222608
CHEMBL1232562
CHEMBL1512075
CHEMBL1741735
CHEMBL1965225
12 / 14 / 11 No. 111 No. 11
C00040673 External link 512 Xanthocillin X
CHEMBL1977264
No. 3069
C00043016 External link 512 Sohirnone C
CHEMBL448004
No. 4087 No. 67
C00043015 External link 512 Sohirnone B
CHEMBL509797
No. 4087 No. 67
C00040674 External link 512 Xanthocillin Y2
No. 5444
C00018758 External link 512 Xanthocillin Y1 permethyl ether
/ 3-Methoxyxanthocillin X dimethyl ether
No. 5444
C00043014 External link 512 Sohirnone A
CHEMBL443858
No. 8248

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00023763 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00023763 0 / 1
P11473 Vitamin D3 receptor NR1I1 C00023763 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00023763 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00023763 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00023763 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00023763 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00023763 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00023763 0 / 1
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00023763 5 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00023763 4 / 3
P31939 Bifunctional purine biosynthesis protein PURH Enzyme C00023763 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#608688 Aicar transformylase/imp cyclohydrolase deficiency P31939
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
#606785 Crigler-najjar syndrome, type ii P22309
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (11)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00208 Hyperbilirubinemia P22309 (related)
H00966 AICA-ribosiduria P31939 (related)
H01171 Poor drug metabolism (PM) P33261 (related)