Species

KNApSAcK Entry

Organism name Gymnopetalum integrifolium
Genus Gymnopetalum
Family Cucurbitaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Gymnopetalum integrifolium
Linked NCBI taxonomy ID 386178
Linked level species

Family

Family in NCBI taxonomy Cucurbitaceae
ID 3650

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00032785 External link 512 Bryoamaride
/ Cucurbitacin l 2-O-beta-D-glucopyranoside
CHEMBL449483
1 / 4 / 2 No. 315
C00032622 External link 512 25-O-Acetylbryoamaride
No. 315
C00032710 External link 512 Aoibaclyin
/ Khekadaengoside G
/ (-)-Khekadaengoside G
No. 315
C00019308 External link 512 Doursterol
/ Daucosterin
/ 3-O-beta-D-Glucopyranosyl sitosterol
/ beta-Sitosterol 3-O-beta-D-glucopyranoside
CHEMBL197711
CHEMBL506678
CHEMBL2304043
C011015
5 / 4 / 2 0 / 3 No. 520

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00019308 0 / 0
P06746 DNA polymerase beta Enzyme C00019308 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00019308 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00019308 0 / 0
P00734 Prothrombin S1A C00019308 4 / 2
P14679 Tyrosinase Oxidoreductase C00032785 4 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (4)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002493 Central Nervous System Diseases C00019308
D003072 Cognition Disorders C00019308
D013118 Spinal Cord Diseases C00019308