PCIDB

Microdesmis keayana

Family in NCBI taxonomy	Pandaceae
ID	124867

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	rosids
ID	71275

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	KCF-S cluster
C00020039	Bonducellin / (E)-7-Hydroxy-3-(4'-methoxybenzylidene)chroman-4-one	CHEMBL450675 CHEMBL1253830		8 / 25 / 23	No. 2899
C00020222	Intricatin / 8-Methoxybonducellin				No. 2899
C00030225	Eucomin	CHEMBL476776		7 / 20 / 19	No. 2899
C00020609	Intricatinol	CHEMBL233805	C061633		No. 2899
C00030604	Keayanine / Keayanine A				No. 3899

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00020039 C00030225	9 / 3
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00020039 C00030225	1 / 8
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00020039 C00030225	0 / 0
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00020039 C00030225	1 / 0
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00020039 C00030225	4 / 3
P11362	Fibroblast growth factor receptor 1	Fgfr	C00020039 C00030225	4 / 5
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00020039 C00030225	2 / 3
O14746	Telomerase reverse transcriptase	Enzyme	C00020039	5 / 5

OMIM	preferred title	UniProt
#207410	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2	P21802
#101200	Apert syndrome	P21802
#609135	Aplastic anemia	O14746
#123790	Beare-stevenson cutis gyrata syndrome; bstvs	P21802
#614592	Bent bone dysplasia syndrome; bbds	P21802
#123500	Crouzon syndrome	P21802
#613989	Dyskeratosis congenita, autosomal dominant, 2; dkca2	O14746
#606764	Gastrointestinal stromal tumor; gist	P10721
#602089	Hemangioma, capillary infantile	P35968
#114550	Hepatocellular carcinoma	P08581
#147950	Hypogonadotropic hypogonadism 2 with or without anosmia; hh2	P11362
#123150	Jackson-weiss syndrome; jws	P21802
#149730	Lacrimoauriculodentodigital syndrome; ladd	P21802
#601626	Leukemia, acute myeloid; aml	P10721
#211980	Lung cancer	P00533
#615134	Melanoma, cutaneous malignant, susceptibility to, 9; cmm9	O14746
#166250	Osteoglophonic dysplasia; ogd	P11362
#101600	Pfeiffer syndrome	P11362 P21802
#172800	Piebald trait; pbt	P10721
#614742	Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1	O14746
#178500	Pulmonary fibrosis, idiopathic; ipf	O14746
#605074	Renal cell carcinoma, papillary, 1; rccp1	P08581
#609579	Scaphocephaly, maxillary retrusion, and mental retardation	P21802
#273300	Testicular germ cell tumor; tgct	P10721
#190440	Trigonocephaly 1; trigno1	P11362

KEGG	name	UniProt
H00764	Cri du chat syndrome	O14746 (related)
H01132	Aplastic anemia (AA)	O14746 (related)
H01299	Idiopathic pulmonary fibrosis	O14746 (related)
H00022	Bladder cancer	O14746 (marker) P00533 (related)
H00024	Prostate cancer	O14746 (marker)
H00016	Oral cancer	P00533 (related) P00533 (marker)
H00017	Esophageal cancer	P00533 (related)
H00018	Gastric cancer	P00533 (related) P08581 (related) P21802 (related)
H00028	Choriocarcinoma	P00533 (related)
H00030	Cervical cancer	P00533 (related)
H00042	Glioma	P00533 (related) P00533 (marker)
H00055	Laryngeal cancer	P00533 (related) P00533 (marker)
H00021	Renal cell carcinoma	P08581 (related)
H00046	Cholangiocarcinoma	P08581 (related)
H00003	Acute myeloid leukemia (AML)	P10721 (related) P10721 (marker)
H00170	Piebaldism	P10721 (related)
H00023	Testicular cancer	P10721 (marker)
H00255	Hypogonadotropic hypogonadism	P11362 (related)
H00443	Osteoglophonic dysplasia (OD)	P11362 (related)
H00458	Craniosynostosis	P11362 (related) P21802 (related)
H00516	Isolated orofacial clefts	P11362 (related)
H01207	Trigonocephaly	P11362 (related)
H00642	Lacrimo-auriculo-dento-digital syndrome (LADD)	P21802 (related)