PCIDB

KNApSAcK Metabolite C00020039

Metabolite

KNApSAcK Entry

id C00020039
Name Bonducellin / (E)-7-Hydroxy-3-(4'-methoxybenzylidene)chroman-4-one
CAS RN 83162-84-9
Standard InChI InChI=1S/C17H14O4/c1-20-14-5-2-11(3-6-14)8-12-10-21-16-9-13(18)4-7-15(16)17(12)19/h2-9,18H,10H2,1H3/b12-8+
Standard InChI (Main Layer) InChI=1S/C17H14O4/c1-20-14-5-2-11(3-6-14)8-12-10-21-16-9-13(18)4-7-15(16)17(12)19/h2-9,18H,10H2,1H3

Cluster

Phytochemical cluster
KCF-S cluster No. 2899

Link

ChEMBL

By standard InChI CHEMBL450675
By standard InChI Main Layer CHEMBL450675 CHEMBL1253830

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P21802 Fibroblast growth factor receptor 2 TK tyrosine-protein kinase TLK subfamily CHEMBL450675 CHEMBL986526 (1)
9 / 3
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily CHEMBL450675 CHEMBL986517 (1)
1 / 11
P12931 Proto-oncogene tyrosine-protein kinase Src Src CHEMBL450675 CHEMBL986511 (1)
0 / 0
P35968 Vascular endothelial growth factor receptor 2 Vegfr CHEMBL450675 CHEMBL986515 (1)
1 / 0
P08581 Hepatocyte growth factor receptor TK tyrosine-protein kinase MET subfamily CHEMBL450675 CHEMBL986512 (1)
2 / 3
P11362 Fibroblast growth factor receptor 1 Fgfr CHEMBL450675 CHEMBL986513 (1)
4 / 5
P10721 Mast/stem cell growth factor receptor Kit Pdgfr CHEMBL450675 CHEMBL986519 (1)
4 / 4
O14746 Telomerase reverse transcriptase Enzyme CHEMBL1253830 CHEMBL1251398 (1)
5 / 5

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (25)

OMIM preferred title UniProt
#207410 Antley-bixler syndrome without genital anomalies or disordered steroidogenesis; abs2 P21802
#101200 Apert syndrome P21802
#609135 Aplastic anemia O14746
#123790 Beare-stevenson cutis gyrata syndrome; bstvs P21802
#614592 Bent bone dysplasia syndrome; bbds P21802
#123500 Crouzon syndrome P21802
#613989 Dyskeratosis congenita, autosomal dominant, 2; dkca2 O14746
#606764 Gastrointestinal stromal tumor; gist P10721
#602089 Hemangioma, capillary infantile P35968
#114550 Hepatocellular carcinoma P08581
#147950 Hypogonadotropic hypogonadism 2 with or without anosmia; hh2 P11362
#123150 Jackson-weiss syndrome; jws P21802
#149730 Lacrimoauriculodentodigital syndrome; ladd P21802
#601626 Leukemia, acute myeloid; aml P10721
#211980 Lung cancer P00533
#615134 Melanoma, cutaneous malignant, susceptibility to, 9; cmm9 O14746
#166250 Osteoglophonic dysplasia; ogd P11362
#101600 Pfeiffer syndrome P11362
P21802
#172800 Piebald trait; pbt P10721
#614742 Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1; pfbmft1 O14746
#178500 Pulmonary fibrosis, idiopathic; ipf O14746
#605074 Renal cell carcinoma, papillary, 1; rccp1 P08581
#609579 Scaphocephaly, maxillary retrusion, and mental retardation P21802
#273300 Testicular germ cell tumor; tgct P10721
#190440 Trigonocephaly 1; trigno1 P11362

KEGG DISEASE (23)

KEGG disease name UniProt
H00764 Cri du chat syndrome O14746 (related)
H01132 Aplastic anemia (AA) O14746 (related)
H01299 Idiopathic pulmonary fibrosis O14746 (related)
H00022 Bladder cancer O14746 (marker)
P00533 (related)
H00024 Prostate cancer O14746 (marker)
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
H00018 Gastric cancer P00533 (related)
P08581 (related)
P21802 (related)
H00028 Choriocarcinoma P00533 (related)
H00030 Cervical cancer P00533 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00021 Renal cell carcinoma P08581 (related)
H00046 Cholangiocarcinoma P08581 (related)
H00003 Acute myeloid leukemia (AML) P10721 (related)
P10721 (marker)
H00170 Piebaldism P10721 (related)
H00023 Testicular cancer P10721 (marker)
H00255 Hypogonadotropic hypogonadism P11362 (related)
H00443 Osteoglophonic dysplasia (OD) P11362 (related)
H00458 Craniosynostosis P11362 (related)
P21802 (related)
H00516 Isolated orofacial clefts P11362 (related)
H01207 Trigonocephaly P11362 (related)
H00642 Lacrimo-auriculo-dento-digital syndrome (LADD) P21802 (related)