Caesalpinia bonduc

• Index
• Plant Species
• Natural Activity
• Metabolite list (27)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Caesalpinia bonduc
Genus	Caesalpinia
Family	Fabaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Guilandina bonduc
Linked NCBI taxonomy ID	191881
Linked level	species

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Natural Activity

List (13)

Species	Activity
Caesalpinia bonduc (L.) Roxb.	Abortifacient
Caesalpinia bonduc (L.) Roxb.	Anthelminthic
Caesalpinia bonduc (L.) Roxb.	Antipyretic
Caesalpinia bonduc (L.) Roxb.	Antispasmodic
Caesalpinia bonduc (L.) Roxb.	Astringent
Caesalpinia bonduc (L.) Roxb.	Diuretic
Caesalpinia bonduc (L.) Roxb.	Emollient
Caesalpinia bonduc (L.) Roxb.	Filaricide
Caesalpinia bonduc (L.) Roxb.	Fungicide
Caesalpinia bonduc (L.) Roxb.	Hemostat
Caesalpinia bonduc (L.) Roxb.	Rubefacient
Caesalpinia bonduc (L.) Roxb.	Tonic
Caesalpinia bonduc (L.) Roxb.	Vermifuge

Metabolite list (27)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00029388	Amarosterol A / 13,14-seco-Stigmasta-5,14-dien-3alpha-ol					No. 53	No. 11
C00029389	Amarosterol B / 13,14-seco-Stigmasta-9(11),14-dien-3alpha-ol					No. 53	No. 11
C00038678	Caesalmin D / (+)-Caesalmin D	CHEMBL464487 CHEMBL517323				No. 146
C00039137	epsilon-Caesalpin / (+)-epsilon-Caesalpin					No. 146
C00036857	Caesalmin B / (+)-Caesalmin B	CHEMBL457149				No. 146
C00029666	alpha-Caesalpin	CHEMBL252323				No. 146
C00029836	Bonducellpin B / (+)-Bonducellpin B					No. 146
C00029837	Bonducellpin C					No. 146
C00029880	Caesalpinin P					No. 146
C00038618	Bonducellpin E / (+)-Bonducellpin E	CHEMBL252118				No. 146
C00029870	Caesalpinin C	CHEMBL465802				No. 146
C00029873	Caesalpinin I					No. 146
C00038620	Bonducellpin G / (+)-Bonducellpin G	CHEMBL400084				No. 146
C00038619	Bonducellpin F / (+)-Bonducellpin F	CHEMBL252322				No. 146
C00029869	Caesalmin E / (+)-Caesalpin H	CHEMBL464487 CHEMBL517323				No. 146
C00029448	2-Acetoxycaesaldekarin e	CHEMBL463937				No. 1064
C00010268	Brazilin	CHEMBL598951 CHEMBL1370456	C044362	32 / 25 / 25		No. 1670
C00029875	Caesalpinin K / (+)-Caesalpinin K					No. 1776
C00031643	Caesaldekarin A / (+)-Caesaldekarin A					No. 1776
C00048341	Caesalpinolide C / (-)-Caesalpinolide C					No. 2146
C00048343	Caesalpinolide E / (-)-Caesalpinolide E	CHEMBL514119				No. 2146
C00029868	Caesaldekarin J					No. 2729
C00020039	Bonducellin / (E)-7-Hydroxy-3-(4'-methoxybenzylidene)chroman-4-one	CHEMBL450675 CHEMBL1253830		8 / 25 / 23		No. 2899
C00048342	Caesalpinolide D / (-)-Caesalpinolide D					No. 3110
C00033244	Neocaesalpin C / (-)-Neocaesalpin C					No. 3252
C00033245	Neocaesalpin D / (+)-Neocaesalpin D					No. 3252
C00031033	Pipataline					No. 7769

Human Protein / Gene in interactions

40 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q99700	Ataxin-2	Unclassified protein	C00010268	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00010268	2 / 0
P21802	Fibroblast growth factor receptor 2	TK tyrosine-protein kinase TLK subfamily	C00020039	9 / 3
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00010268	0 / 0
P14735	Insulin-degrading enzyme	Enzyme	C00010268	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00010268	3 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00020039	1 / 8
P11473	Vitamin D3 receptor	NR1I1	C00010268	2 / 3
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00010268	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00010268	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00010268	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00010268	2 / 0
O75496	Geminin	Unclassified protein	C00010268	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00010268	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00010268	1 / 1
P11308	Transcriptional regulator ERG	Unclassified protein	C00010268	1 / 2
P83916	Chromobox protein homolog 1	Unclassified protein	C00010268	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00010268	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00010268	0 / 0
P12931	Proto-oncogene tyrosine-protein kinase Src	Src	C00020039	0 / 0
P35968	Vascular endothelial growth factor receptor 2	Vegfr	C00020039	1 / 0
P08581	Hepatocyte growth factor receptor	TK tyrosine-protein kinase MET subfamily	C00020039	2 / 3
P28482	Mitogen-activated protein kinase 1	Erk	C00010268	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00010268	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00010268	2 / 2
P11362	Fibroblast growth factor receptor 1	Fgfr	C00020039	4 / 5
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00010268	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00010268	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00010268	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00010268	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00010268	0 / 0
P10721	Mast/stem cell growth factor receptor Kit	Pdgfr	C00020039	4 / 3
O14746	Telomerase reverse transcriptase	Enzyme	C00020039	5 / 5
Q9UBT6	DNA polymerase kappa	Enzyme	C00010268	0 / 0
Q14145	Kelch-like ECH-associated protein 1	Unclassified protein	C00010268	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00010268	0 / 0
O00255	Menin	Unclassified protein	C00010268	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00010268	1 / 2
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00010268	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00010268	2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions