Species

KNApSAcK Entry

Organism name Merulius tremellosus
Genus Merulius
Family Meruliaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Phlebia tremellosa
Linked NCBI taxonomy ID 98777
Linked level species

Family

Family in NCBI taxonomy Corticiaceae
ID 5304

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029679 External link 512 alpha-Bisabolol
CHEMBL519167
CHEMBL491186
CHEMBL477832
CHEMBL1096927
CHEMBL1171719
CHEMBL1561544
CHEMBL2104360
C004497
8 / 4 / 13 No. 541 No. 38
C00021523 External link 512 Merulanic acid
No. 2606
C00021522 External link 512 Merulactone
No. 2606
C00021479 External link 512 (+)-Tremetriol
No. 2686
C00021477 External link 512 (-)-Tremediol
No. 2686

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00029679 0 / 3
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00029679 1 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00029679 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00029679 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00029679 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00029679 0 / 1
O00255 Menin Unclassified protein C00029679 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00029679 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)