PCIDB

Tabernaemontana divaricata (L.)R.Br.

Species

KNApSAcK Entry

Organism name Tabernaemontana divaricata (L.)R.Br.
Genus Tabernaemontana
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tabernaemontana
Linked NCBI taxonomy ID 52860
Linked level genus

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00024457 External link 512 Lochnericine
/ (-)-Lochnericine
CHEMBL2011514
No. 61 No. 4
C00025917 External link 512 Isovoacristine
CHEMBL184378
CHEMBL360973
No. 250 No. 4
C00025752 External link 512 5-Hydroxy-6-oxocoronaridine
No. 250 No. 4
C00025754 External link 512 5-Oxocoronaridine
No. 250 No. 4
C00025757 External link 512 6-Oxocoronaridine
No. 250 No. 4
C00024619 External link 512 Voaphyllin
/ Conoflorin
/ Conoflorine
/ Voaphylline
/ (+)-Conoflorine
/ (+)-Voaphylline
CHEMBL496674
No. 828
C00025859 External link 512 Dregamine
/ (-)-Dregamine
/ 20-Epitabernemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771
C00026055 External link 512 20-Epidregamine
/ Tabernaemontanin
/ Tabernaemontanine
/ (-)-Tabernemontanine
/ (-)-Tabernaemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00025859 C00026055 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00025859 C00026055 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00025859 C00026055 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00025859 C00026055 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00025859 C00026055 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00025859 C00026055 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00025859 C00026055 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025859 C00026055 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00025859 C00026055 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)