Species

KNApSAcK Entry

Organism name Murraya siamensis Craib
Genus Murraya
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Murraya siamensis
Linked NCBI taxonomy ID 159029
Linked level species

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025143 External link 512 3-Formyl-2,7-dimethoxy carbazole
CHEMBL1689805
No. 239
C00025140 External link 512 2-Hydroxy-3-formyl-7-methoxycarbazole
CHEMBL463264
No. 239
C00024679 External link 512 7-Methoxyheptaphylline
No. 437
C00025172 External link 512 Heptaphylline
CHEMBL1689799
No. 437
C00025171 External link 512 NSC 94932
/ Girinimbin
/ Girinimbine
CHEMBL1477760
C034052
16 / 17 / 43 No. 516
C00024718 External link 512 Mukonal
CHEMBL1077147
No. 751
C00025144 External link 512 3-Formyl-2-methoxy carbazole
No. 6976

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor C00025171 7 / 37
P17861 X-box-binding protein 1 Unclassified protein C00025171 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00025171 0 / 0
P06746 DNA polymerase beta Enzyme C00025171 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00025171 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00025171 2 / 0
O75496 Geminin Unclassified protein C00025171 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00025171 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00025171 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00025171 1 / 2
O15118 Niemann-Pick C1 protein Unclassified protein C00025171 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00025171 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00025171 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00025171 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00025171 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00025171 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114500 Colorectal cancer; crc P84022
#133239 Esophageal cancer P04637
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#612371 Major affective disorder 7; mafd7 P17861
#257220 Niemann-pick disease, type c1; npc1 O15118
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (43)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)