Species

KNApSAcK Entry

Organism name Aconitum flavum
Genus Aconitum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aconitum flavum
Linked NCBI taxonomy ID 286045
Linked level species

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00024821 External link 512 1-epi-Napelline
/ 1-Epiluciculine
/ 1-Epinapelline
CHEMBL1487558
CHEMBL1741394
9 / 3 / 5 No. 124 No. 10
C00024887 External link 512 Flavamine
/ Napelline beta-N-oxide
No. 1349
C00024886 External link 512 Flavadine
/ O15-Acetylnapelline beta-N-oxide
No. 1349
C00024933 External link 512 Flavamine
/ Napelline N-oxide
/ Napelline b-N-oxide
No. 1349

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00024821 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00024821 0 / 1
P11308 Transcriptional regulator ERG Unclassified protein C00024821 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00024821 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00024821 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00024821 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00024821 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00024821 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00024821 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#612219 Ewing sarcoma; es P11308

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)