KCF-S cluster No. 124 (42 metabolites)
Corresponding Phytochemical cluster No. 10
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| eudicotyledons | 78 |
| rosids | 2 |
Cumulative family count
| class name | count |
|---|---|
| Ranunculaceae | 78 |
| Rosaceae | 2 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Terpenoid alkaloids | 3 |
metabolites link (5)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Terpenoid alkaloids | C08680 | C00001636 |
| Terpenoid alkaloids | C08700 | C00001656 |
| Terpenoid alkaloids | C08707 | C00001663 |
| Terpenoid alkaloids | C08707 | C00024934 |
| Terpenoid alkaloids | C08680 | C00028165 |
Metabolite list (42)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001636
|
Denudatine
|
C034767
|
|
|||
|
C00001656
|
Napelline
/ Luciculine |
CHEMBL1487558
CHEMBL1741394 |
C109326
|
9 / 3 / 5 |
|
|
|
C00001663
|
Songorin
/ Napellonin / Napellonine / Bullatine G |
CHEMBL1895895
CHEMBL2165580 |
C057217
|
1 / 0 / 0 |
|
|
|
C00024799
|
11-Acetyl-1,19-epoxydenudatine
/ 1,19-Epoxydenudatine 11-acetate |
|
||||
|
C00024801
|
11alpha-Hydroxylepenine
|
|
||||
|
C00024803
|
12-Acetyldehydrolucidusculine
/ Dehydrolucidusculine 12-acetate |
|
||||
|
C00024804
|
12-Acetylnapelline
/ 12-O-Acetylnapelline |
CHEMBL252513
|
|
|||
|
C00024806
|
12-Epiacetyldehydronapelline
/ 12-epi-Acetyldehydronapelline / 12-Epidehydronapelline 12-acetate |
|
||||
|
C00024807
|
12-Epinapelline
/ 12-Epiluciculine / 12-epi-Napelline |
CHEMBL1487558
CHEMBL1741394 |
9 / 3 / 5 |
|
||
|
C00024815
|
Acetylsongorine
/ 15-Acetylsongorine / 15-Acetylzongorine / Songorine 15-acetate / 15-O-Acetylsongorine / Zongorine 15-acetate |
|
||||
|
C00024821
|
1-epi-Napelline
/ 1-Epiluciculine / 1-Epinapelline |
CHEMBL1487558
CHEMBL1741394 |
9 / 3 / 5 |
|
||
|
C00024830
|
Actaline
/ (+)-Actaline |
|
||||
|
C00024831
|
Ajabicine
|
|
||||
|
C00024833
|
Andersobine
|
|
||||
|
C00024867
|
Dehydrolucidusculine
/ 1-Deoxy-1,19-epoxylucidusculine |
CHEMBL403781
|
|
|||
|
C00024868
|
Dehydronapelline
|
|
||||
|
C00024869
|
Dehydrosongorine
|
|
||||
|
C00024884
|
Finetianine
|
|
||||
|
C00024903
|
Gymnandine
|
C082776
|
|
|||
|
C00024916
|
Jynosine
/ 15-acetyl denudatine / Denudatine 15-acetate |
|
||||
|
C00024918
|
Kirinine A
|
|
||||
|
C00024919
|
Kirinine B
|
|
||||
|
C00024924
|
Lepedine
|
C054802
|
|
|||
|
C00024925
|
Lepenine
|
C054803
|
|
|||
|
C00024927
|
Lepetine
/ 11-acetyllepenine / 11-O-Acetyllepenine |
C054804
|
|
|||
|
C00024928
|
Liangshanine
/ (-)-Liangshanine |
|
||||
|
C00024929
|
Liangshanone
/ (-)-Liangshanone |
|
||||
|
C00024934
|
Songorin
/ Zongorine / Napellonine |
CHEMBL1895895
CHEMBL2165580 |
C057217
|
1 / 0 / 0 |
|
|
|
C00024935
|
N-deethyldehydrolucidusculine
|
|
||||
|
C00024937
|
Norsongoramine
|
|
||||
|
C00024938
|
Norsongorine
/ N-Deethylsongorine |
|
||||
|
C00024959
|
Songoramine
/ Zongoramine |
|
||||
|
C00024967
|
Spirafine II
|
|
||||
|
C00024968
|
Spirafine III
|
|
||||
|
C00025018
|
Subdesculine
/ Anhydroepoxynapelline 12-acetate |
|
||||
|
C00025026
|
Turpelline
/ 11beta-Hydroxynapelline |
|
||||
|
C00025035
|
Vilmorinianine
|
|
||||
|
C00027666
|
12-epi-Dehydronapelline
/ (+)-12-Epidehydronapelline |
|
||||
|
C00027668
|
12-Epinapelline
/ (-)-12-Epinapelline |
CHEMBL1487558
CHEMBL1741394 |
9 / 3 / 5 |
|
||
|
C00028165
|
Denudatine
|
C034767
|
|
|||
|
C00028458
|
Lepenine
|
C054803
|
|
|||
|
C00038133
|
12-Acetyllucidusculine
|
CHEMBL402498
CHEMBL2137662 |
2 / 1 / 1 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001656 C00024807 C00024821 C00027668 | 1 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001656 C00024807 C00024821 C00027668 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001656 C00024807 C00024821 C00027668 | 0 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001656 C00024807 C00024821 C00027668 | 0 / 1 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00001656 C00024807 C00024821 C00027668 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001656 C00024807 C00024821 C00027668 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001656 C00024807 C00024821 C00027668 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001656 C00024807 C00024821 C00027668 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001656 C00024807 C00024821 C00027668 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001663 C00024934 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00038133 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00038133 | 1 / 1 |