Species

KNApSAcK Entry

Organism name Sesbania drummondii
Genus Sesbania
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Sesbania drummondii
Linked NCBI taxonomy ID 206308
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000701 External link 512 Justicidin B
No. 285 No. 21
C00047211 External link 512 Cycloheximide
CHEMBL123292
CHEMBL356004
CHEMBL225699
CHEMBL600517
CHEMBL582062
CHEMBL1078564
CHEMBL1358722
CHEMBL1552697
D003513
131 / 80 / 80 286 / 16 No. 2705
C00018681 External link 512 NSC 66645
/ Protomycin
/ Streptimidon
/ Streptimidone
CHEMBL1981837
C005258
No. 4062
C00043471 External link 512 Drummondol
CHEMBL454176
C029812
No. 4252
C00047352 External link 512 Sesbanimide B
CHEMBL560362
CHEMBL1965002
No. 5600
C00047351 External link 512 Sesbanimide A
/ (+)-Sesbanimide A
CHEMBL560362
CHEMBL1965002
C077293
No. 5600
C00047353 External link 512 Sesbanimide C
No. 5816

Human Protein / Gene in interactions

131 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00047211 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00047211 7 / 37
Q16637 Survival motor neuron protein Unclassified protein C00047211 4 / 1
P17861 X-box-binding protein 1 Unclassified protein C00047211 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00047211 0 / 0
Q99700 Ataxin-2 Unclassified protein C00047211 1 / 1
P21728 D(1A) dopamine receptor Dopamine receptor C00047211 0 / 0
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00047211 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00047211 0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00047211 2 / 2
P08246 Neutrophil elastase S1A C00047211 2 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00047211 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00047211 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00047211 0 / 0
P29466 Caspase-1 C14 C00047211 0 / 0
P17252 Protein kinase C alpha type Alpha C00047211 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00047211 0 / 0
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00047211 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00047211 2 / 2
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00047211 0 / 0
P02545 Prelamin-A/C Unclassified protein C00047211 11 / 10
P37840 Alpha-synuclein Unclassified protein C00047211 4 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00047211 3 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00047211 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00047211 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00047211 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00047211 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00047211 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00047211 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00047211 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00047211 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00047211 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00047211 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00047211 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00047211 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00047211 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00047211 0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00047211 1 / 8
P11473 Vitamin D3 receptor NR1I1 C00047211 2 / 3
P14416 D(2) dopamine receptor Dopamine receptor C00047211 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00047211 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00047211 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00047211 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00047211 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00047211 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00047211 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00047211 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00047211 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00047211 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00047211 0 / 0
Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 Enzyme C00047211 0 / 0
Q00688 Peptidyl-prolyl cis-trans isomerase FKBP3 Enzyme C00047211 0 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00047211 0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00047211 0 / 0
P42858 Huntingtin Unclassified protein C00047211 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00047211 2 / 0
O75496 Geminin Unclassified protein C00047211 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00047211 0 / 0
P13639 Elongation factor 2 Unclassified protein C00047211 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00047211 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00047211 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00047211 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00047211 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00047211 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00047211 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00047211 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00047211 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00047211 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00047211 0 / 0
P10145 Interleukin-8 Secreted protein C00047211 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00047211 1 / 0
Q9Y237 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 Enzyme C00047211 0 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00047211 0 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00047211 0 / 0
P08311 Cathepsin G S1A C00047211 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00047211 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00047211 0 / 0
Q9NWM8 Peptidyl-prolyl cis-trans isomerase FKBP14 Enzyme C00047211 1 / 0
P03956 Interstitial collagenase M10A C00047211 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00047211 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00047211 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00047211 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00047211 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00047211 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00047211 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00047211 2 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00047211 5 / 3
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00047211 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00047211 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00047211 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00047211 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00047211 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00047211 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00047211 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00047211 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00047211 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00047211 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00047211 0 / 0
P27540 Aryl hydrocarbon receptor nuclear translocator Unclassified protein C00047211 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00047211 1 / 1
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00047211 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00047211 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00047211 0 / 0
P03372 Estrogen receptor NR3A1 C00047211 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00047211 1 / 0
P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A Isomerase C00047211 0 / 0
P22303 Acetylcholinesterase Hydrolase C00047211 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00047211 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00047211 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00047211 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00047211 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00047211 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00047211 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00047211 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00047211 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00047211 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00047211 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00047211 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00047211 0 / 0
P10275 Androgen receptor NR3C4 C00047211 3 / 4
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00047211 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00047211 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00047211 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00047211 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00047211 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00047211 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00047211 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00047211 0 / 0
P68104 Elongation factor 1-alpha 1 Unclassified protein C00047211 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00047211 1 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00047211 1 / 1

286 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00047211
5244 ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3 ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44) C00047211
8714 ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 C00047211
10057 ABCC5, ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 C00047211
2181 ACSL3, ACS3, FACL3, PRO2194 acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3) C00047211
8754 ADAM9, CORD9, MCMP, MDC9, Mltng ADAM metallopeptidase domain 9 C00047211
133 ADM, AM adrenomedullin C00047211
136 ADORA2B, ADORA2 adenosine A2b receptor C00047211
196 AHR, bHLHe76 aryl hydrocarbon receptor C00047211
9495 AKAP5, AKAP75, AKAP79, H21 A kinase (PRKA) anchor protein 5 C00047211
9472 AKAP6, ADAP100, ADAP6, AKAP100, PRKA6, mAKAP A kinase (PRKA) anchor protein 6 C00047211
220 ALDH1A3, ALDH1A6, ALDH6, MCOP8, RALDH3 aldehyde dehydrogenase 1 family, member A3 (EC:1.2.1.5) C00047211
224 ALDH3A2, ALDH10, FALDH, SLS aldehyde dehydrogenase 3 family, member A2 (EC:1.2.1.3) C00047211
241 ALOX5AP, FLAP arachidonate 5-lipoxygenase-activating protein C00047211
248 ALPI, IAP alkaline phosphatase, intestinal (EC:3.1.3.1) C00047211
269 AMHR2, AMHR, MISR2, MISRII, MRII anti-Mullerian hormone receptor, type II (EC:2.7.11.30) C00047211
287 ANK2, ANK-2, LQT4, brank-2 ankyrin 2, neuronal C00047211
84079 ANKRD27, VARP ankyrin repeat domain 27 (VPS9 domain) C00047211
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00047211
374 AREG, AR, CRDGF, SDGF amphiregulin C00047211
79798 ARMC5 armadillo repeat containing 5 C00047211
51665 ASB1, ASB-1 ankyrin repeat and SOCS box containing 1 C00047211
468 ATF4, CREB-2, CREB2, TAXREB67, TXREB activating transcription factor 4 C00047211
552 AVPR1A, AVPR_V1a, AVPR1, V1aR arginine vasopressin receptor 1A C00047211
8424 BBOX1, BBH, BBOX, G-BBH, gamma-BBH butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 (EC:1.14.11.1) C00047211
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00047211
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00047211
79370 BCL2L14, BCLG BCL2-like 14 (apoptosis facilitator) C00047211
622 BDH1, BDH, SDR9C1 3-hydroxybutyrate dehydrogenase, type 1 (EC:1.1.1.30) C00047211
8678 BECN1, ATG6, VPS30, beclin1 beclin 1, autophagy related C00047211
637 BID, FP497 BH3 interacting domain death agonist C00047211
672 BRCA1, BRCAI, BRCC1, BROVCA1, IRIS, PNCA4, PPP1R53, PSCP, RNF53 breast cancer 1, early onset C00047211
675 BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1, GLM3, PNCA2 breast cancer 2, early onset C00047211
90488 C12orf23 chromosome 12 open reading frame 23 C00047211
793 CALB1, CALB calbindin 1, 28kDa C00047211
819 CAMLG, CAML calcium modulating ligand C00047211
834 CASP1, ICE, IL1BC, P45 caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) C00047211
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00047211
837 CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57) C00047211
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00047211
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00047211
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00047211
857 CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV caveolin 1, caveolae protein, 22kDa C00047211
10951 CBX1, CBX, HP1-BETA, HP1Hs-beta, HP1Hsbeta, M31, MOD1, p25beta chromobox homolog 1 C00047211
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00047211
6352 CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP chemokine (C-C motif) ligand 5 C00047211
890 CCNA2, CCN1, CCNA cyclin A2 C00047211
595 CCND1, BCL1, D11S287E, PRAD1, U21B31 cyclin D1 C00047211
22948 CCT5, CCT-epsilon, CCTE, TCP-1-epsilon chaperonin containing TCP1, subunit 5 (epsilon) C00047211
952 CD38, T10 CD38 molecule (EC:3.2.2.5) C00047211
916 CD3E, T3E, TCRE CD3e molecule, epsilon (CD3-TCR complex) C00047211
961 CD47, IAP, MER6, OA3 CD47 molecule C00047211
967 CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30 CD63 molecule C00047211
925 CD8A, CD8, Leu2, MAL, p32 CD8a molecule C00047211
56990 CDC42SE2, SPEC2 CDC42 small effector 2 C00047211
113130 CDCA5, SORORIN cell division cycle associated 5 C00047211
1017 CDK2, p33(CDK2) cyclin-dependent kinase 2 (EC:2.7.11.22) C00047211
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00047211
1029 CDKN2A, ARF, CDK4I, CDKN2, CMM2, INK4, INK4A, MLM, MTS-1, MTS1, P14, P14ARF, P16, P16-INK4A, P16INK4, P16INK4A, P19, P19ARF, TP16 cyclin-dependent kinase inhibitor 2A C00047211
8837 CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS CASP8 and FADD-like apoptosis regulator C00047211
1128 CHRM1, HM1, M1, M1R cholinergic receptor, muscarinic 1 C00047211
10370 CITED2, ASD8, MRG-1, MRG1, P35SRJ, VSD2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 C00047211
1182 CLCN3, CLC3, ClC-3 chloride channel, voltage-sensitive 3 C00047211
1268 CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR cannabinoid receptor 1 (brain) C00047211
51084 CRYL1, GDH, lambda-CRY crystallin, lambda 1 (EC:1.1.1.45) C00047211
1437 CSF2, GMCSF colony stimulating factor 2 (granulocyte-macrophage) C00047211
1453 CSNK1D, ASPS, CKIdelta, FASPS2, HCKID casein kinase 1, delta (EC:2.7.11.1 2.7.11.26) C00047211
1490 CTGF, CCN2, HCS24, IGFBP8, NOV2 connective tissue growth factor C00047211
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00047211
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00047211
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00047211
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00047211
1591 CYP24A1, CP24, CYP24, HCAI, P450-CC24 cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126) C00047211
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00047211
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00047211
1572 CYP2F1, C2F1, CYP2F cytochrome P450, family 2, subfamily F, polypeptide 1 (EC:1.14.14.1) C00047211
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00047211
3491 CYR61, CCN1, GIG1, IGFBP10 cysteine-rich, angiogenic inducer, 61 C00047211
1605 DAG1, 156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9 dystroglycan 1 (dystrophin-associated glycoprotein 1) C00047211
1634 DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B decorin C00047211
10522 DEAF1, NUDR, SPN, ZMYND5 DEAF1 transcription factor C00047211
8560 DEGS1, DEGS, DEGS-1, DES1, Des-1, FADS7, MLD delta(4)-desaturase, sphingolipid 1 (EC:1.14.-.-) C00047211
1734 DIO2, 5DII, D2, DIOII, SelY, TXDI2 deiodinase, iodothyronine, type II (EC:1.97.1.10) C00047211
8847 DLEU2, 1B4, BCMSUN, DLB2, LEU2, LINC00022, MIR15AHG, NCRNA00022, RFP2OS, TRIM13OS deleted in lymphocytic leukemia 2 (non-protein coding) C00047211
25822 DNAJB5, Hsc40 DnaJ (Hsp40) homolog, subfamily B, member 5 C00047211
10059 DNM1L, DLP1, DRP1, DVLP, DYMPLE, EMPF, HDYNIV dynamin 1-like (EC:3.6.5.5) C00047211
1956 EGFR, ERBB, ERBB1, HER1, PIG61, mENA epidermal growth factor receptor (EC:2.7.10.1) C00047211
1958 EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 early growth response 1 C00047211
1959 EGR2, AT591, CMT1D, CMT4E, KROX20 early growth response 2 C00047211
83939 EIF2A, EIF-2A, MST089, MSTP004, MSTP089 eukaryotic translation initiation factor 2A, 65kDa C00047211
1965 EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa C00047211
8672 EIF4G3, eIF-4G_3, eIF4G_3, eIF4GII eukaryotic translation initiation factor 4 gamma, 3 C00047211
1983 EIF5, EIF-5, EIF-5A eukaryotic translation initiation factor 5 C00047211
2000 ELF4, ELFR, MEF E74-like factor 4 (ets domain transcription factor) C00047211
2002 ELK1 ELK1, member of ETS oncogene family C00047211
8507 ENC1, CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10 ectodermal-neural cortex 1 (with BTB domain) C00047211
2021 ENDOG endonuclease G C00047211
1833 EPYC, DSPG3, PGLB, Pg-Lb, SLRR3B epiphycan C00047211
2064 ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN_19, NEU, NGL, TKR1 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (EC:2.7.10.1) C00047211
2065 ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) C00047211
2069 EREG, ER epiregulin C00047211
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00047211
2132 EXT2, SOTV exostosin glycosyltransferase 2 (EC:2.4.1.225 2.4.1.224) C00047211
2161 F12, HAE3, HAEX, HAF coagulation factor XII (Hageman factor) (EC:3.4.21.38) C00047211
2147 F2, PT, RPRGL2, THPH1 coagulation factor II (thrombin) (EC:3.4.21.5) C00047211
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00047211
356 FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 Fas ligand (TNF superfamily, member 6) C00047211
2194 FASN, FAS, OA-519, SDR27X1 fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39) C00047211
2091 FBL, FIB, FLRN, RNU3IP1 fibrillarin C00047211
10875 FGL2, T49, pT49 fibrinogen-like 2 C00047211
2272 FHIT, AP3Aase, FRA3B fragile histidine triad (EC:3.6.1.29) C00047211
2277 FIGF, VEGF-D, VEGFD c-fos induced growth factor (vascular endothelial growth factor D) C00047211
2332 FMR1, FMRP, FRAXA, POF, POF1 fragile X mental retardation 1 C00047211
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00047211
2444 FRK, GTK, PTK5, RAK fyn-related kinase (EC:2.7.10.2) C00047211
10468 FST, FS follistatin C00047211
2526 FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, LeX, SSEA-1 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-) C00047211
8324 FZD7, FzE3 frizzled family receptor 7 C00047211
2589 GALNT1, GALNAC-T1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (EC:2.4.1.41) C00047211
2619 GAS1 growth arrest-specific 1 C00047211
9518 GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB growth differentiation factor 15 C00047211
8733 GPAA1, GAA1, hGAA1 glycosylphosphatidylinositol anchor attachment 1 C00047211
2861 GPR37, EDNRBL, PAELR, hET(B)R-LP G protein-coupled receptor 37 (endothelin receptor type B-like) C00047211
2896 GRN, CLN11, GEP, GP88, PCDGF, PEPI, PGRN granulin C00047211
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00047211
1839 HBEGF, DTR, DTS, DTSF, HEGFL heparin-binding EGF-like growth factor C00047211
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00047211
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00047211
3188 HNRNPH2, FTP3, HNRPH', HNRPH2, hnRNPH' heterogeneous nuclear ribonucleoprotein H2 (H') C00047211
10553 HTATIP2, CC3, SDR44U1, TIP30 HIV-1 Tat interactive protein 2, 30kDa (EC:1.1.1.-) C00047211
3383 ICAM1, BB2, CD54, P3.58 intercellular adhesion molecule 1 C00047211
8870 IER3, DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 immediate early response 3 C00047211
2537 IFI6, 6-16, FAM14C, G1P3, IFI-6-16, IFI616 interferon, alpha-inducible protein 6 C00047211
3440 IFNA2, IFN-alphaA, IFNA, IFNA2B, INFA2 interferon, alpha 2 C00047211
3458 IFNG, IFG, IFI interferon, gamma C00047211
11020 IFT27, RABL4, RAYL intraflagellar transport 27 homolog (Chlamydomonas) C00047211
3487 IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 insulin-like growth factor binding protein 4 C00047211
3552 IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 interleukin 1, alpha C00047211
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00047211
3569 IL6, BSF2, HGF, HSF, IFNB2, IL-6 interleukin 6 (interferon, beta 2) C00047211
3572 IL6ST, CD130, CDW130, GP130, IL-6RB interleukin 6 signal transducer (gp130, oncostatin M receptor) C00047211
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00047211
8826 IQGAP1, HUMORFA01, SAR1, p195 IQ motif containing GTPase activating protein 1 C00047211
3667 IRS1, HIRS-1 insulin receptor substrate 1 C00047211
3690 ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) C00047211
3694 ITGB6 integrin, beta 6 C00047211
3705 ITPK1, ITRPK1 inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) C00047211
3708 ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29 inositol 1,4,5-trisphosphate receptor, type 1 C00047211
23189 KANK1, ANKRD15, CPSQ2, KANK KN motif and ankyrin repeat domains 1 C00047211
23313 C22orf9 KIAA0930 C00047211
3845 KRAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2 Kirsten rat sarcoma viral oncogene homolog C00047211
3860 KRT13, CK13, K13 keratin 13 C00047211
200185 KRTCAP2, KCP2 keratinocyte associated protein 2 C00047211
3932 LCK, LSK, YT16, p56lck, pp58lck lymphocyte-specific protein tyrosine kinase (EC:2.7.10.2) C00047211
3958 LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2 lectin, galactoside-binding, soluble, 3 C00047211
4008 LMO7, FBX20, FBXO20, LOMP LIM domain 7 C00047211
9404 LPXN, LDPL leupaxin C00047211
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00047211
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00047211
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00047211
5598 MAPK7, BMK1, ERK4, ERK5, PRKM7 mitogen-activated protein kinase 7 (EC:2.7.11.24) C00047211
4170 MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT myeloid cell leukemia sequence 1 (BCL2-related) C00047211
4192 MDK, ARAP, MK, NEGF2 midkine (neurite growth-promoting factor 2) C00047211
406991 MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21 microRNA 21 C00047211
4312 MMP1, CLG, CLGN matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) C00047211
4322 MMP13, CLG3, MANDP1 matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-) C00047211
3110 MNX1, HB9, HLXB9, HOXHB9, SCRA1 motor neuron and pancreas homeobox 1 C00047211
4350 MPG, AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg N-methylpurine-DNA glycosylase (EC:3.2.2.21) C00047211
51081 MRPS7, MRP-S, MRP-S7, RP-S7, RPMS7, S7mt, bMRP27a mitochondrial ribosomal protein S7 C00047211
4437 MSH3, DUP, MRP1 mutS homolog 3 C00047211
4481 MSR1, CD204, SCARA1, SR-A, SRA, phSR1, phSR2 macrophage scavenger receptor 1 C00047211
23788 MTCH2, MIMP, SLC25A50 mitochondrial carrier 2 C00047211
9108 MTMR7 myotubularin related protein 7 (EC:3.1.3.-) C00047211
4084 MXD1, BHLHC58, MAD, MAD1 MAX dimerization protein 1 C00047211
83463 MXD3, BHLHC13, MAD3, MYX MAX dimerization protein 3 C00047211
4638 MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK myosin light chain kinase (EC:2.7.11.18) C00047211
4077 NBR1, 1A1-3B, M17S2 neighbor of BRCA1 gene 1 C00047211
4751 NEK2, HsPK21, NEK2A, NLK1 NIMA-related kinase 2 (EC:2.7.11.1) C00047211
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00047211
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00047211
4792 NFKBIA, IKBA, MAD-3, NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha C00047211
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00047211
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00047211
4856 NOV, CCN3, IBP-9, IGFBP-9, IGFBP9, NOVh nephroblastoma overexpressed C00047211
4886 NPY1R, NPY1-R, NPYR neuropeptide Y receptor Y1 C00047211
10062 NR1H3, LXR-a, LXRA, RLD-1 nuclear receptor subfamily 1, group H, member 3 C00047211
64710 NUCKS1, NUCKS nuclear casein kinase and cyclin-dependent kinase substrate 1 C00047211
4986 OPRK1, K-OR-1, KOR, KOR-1, OPRK opioid receptor, kappa 1 C00047211
4988 OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM opioid receptor, mu 1 C00047211
5036 PA2G4, EBP1, HG4-1, p38-2G4 proliferation-associated 2G4, 38kDa C00047211
5069 PAPPA, ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1 pregnancy-associated plasma protein A, pappalysin 1 (EC:3.4.24.79) C00047211
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00047211
5077 PAX3, CDHS, HUP2, WS1, WS3 paired box 3 C00047211
84759 PCGF1, 2010002K04Rik, NSPC1, RNF3A-2, RNF68 polycomb group ring finger 1 C00047211
5111 PCNA proliferating cell nuclear antigen C00047211
5134 PDCD2, RP8, ZMYND7 programmed cell death 2 C00047211
5297 PI4KA, PI4K-ALPHA, PIK4CA, pi4K230 phosphatidylinositol 4-kinase, catalytic, alpha (EC:2.7.1.67) C00047211
5283 PIGH, GPI-H phosphatidylinositol glycan anchor biosynthesis, class H (EC:2.4.1.198) C00047211
10026 PIGK, GPI8 phosphatidylinositol glycan anchor biosynthesis, class K (EC:3.-.-.-) C00047211
5289 PIK3C3, VPS34, hVps34 phosphatidylinositol 3-kinase, catalytic subunit type 3 (EC:2.7.1.137) C00047211
5294 PIK3CG, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (EC:2.7.11.1 2.7.1.153) C00047211
29990 PILRB, FDFACT1, FDFACT2 paired immunoglobin-like type 2 receptor beta C00047211
5319 PLA2G1B, PLA2, PLA2A, PPLA2 phospholipase A2, group IB (pancreas) (EC:3.1.1.4) C00047211
5329 PLAUR, CD87, U-PAR, UPAR, URKR plasminogen activator, urokinase receptor C00047211
23646 PLD3, HU-K4, HUK4 phospholipase D family, member 3 (EC:3.1.4.4) C00047211
5350 PLN, CMD1P, CMH18, PLB phospholamban C00047211
5366 PMAIP1, APR, NOXA phorbol-12-myristate-13-acetate-induced protein 1 C00047211
10908 PNPLA6, NTE, NTEMND, SPG39, iPLA2delta, sws patatin-like phospholipase domain containing 6 (EC:3.1.1.5) C00047211
56342 PPAN, BXDC3, SSF, SSF-1, SSF1, SSF2 peter pan homolog (Drosophila) C00047211
5532 PPP3CB, CALNA2, CALNB, CNA2, PP2Bbeta protein phosphatase 3, catalytic subunit, beta isozyme (EC:3.1.3.16) C00047211
10549 PRDX4, AOE37-2, PRX-4 peroxiredoxin 4 (EC:1.11.1.15) C00047211
5579 PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2 protein kinase C, beta (EC:2.7.11.13) C00047211
5590 PRKCZ, PKC-ZETA, PKC2 protein kinase C, zeta (EC:2.7.11.13) C00047211
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00047211
5743 PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) C00047211
5764 PTN, HARP, HBGF8, HBNF, NEGF1 pleiotrophin C00047211
7803 PTP4A1, HH72, PRL-1, PRL1, PTP(CAAX1), PTPCAAX1 protein tyrosine phosphatase type IVA, member 1 (EC:3.1.3.48) C00047211
11156 PTP4A3, PRL-3, PRL-R, PRL3 protein tyrosine phosphatase type IVA, member 3 (EC:3.1.3.48) C00047211
2889 RAPGEF1, C3G, GRF2 Rap guanine nucleotide exchange factor (GEF) 1 C00047211
5919 RARRES2, HP10433, TIG2 retinoic acid receptor responder (tazarotene induced) 2 C00047211
5933 RBL1, CP107, PRB1, p107 retinoblastoma-like 1 (p107) C00047211
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00047211
5972 REN, HNFJ2 renin (EC:3.4.23.15) C00047211
51065 RPS27L ribosomal protein S27-like C00047211
6283 S100A12, CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6 S100 calcium binding protein A12 C00047211
6275 S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98 S100 calcium binding protein A4 C00047211
6278 S100A7, PSOR1, S100A7c S100 calcium binding protein A7 C00047211
6303 SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1 spermidine/spermine N1-acetyltransferase 1 (EC:2.3.1.57) C00047211
90701 SEC11C, SEC11L3, SPC21, SPCS4C SEC11 homolog C (S. cerevisiae) (EC:3.4.21.89) C00047211
5272 SERPINB9, CAP-3, CAP3, PI-9, PI9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 C00047211
5054 SERPINE1, PAI, PAI-1, PAI1, PLANH1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 C00047211
5270 SERPINE2, GDN, GDNPF, PI-7, PI7, PN-1, PN1, PNI serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 C00047211
9792 SERTAD2, Sei-2, TRIP-Br2 SERTA domain containing 2 C00047211
140885 SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP signal-regulatory protein alpha (EC:3.1.3.48) C00047211
6503 SLA, SLA1, SLAP Src-like-adaptor C00047211
6566 SLC16A1, HHF7, MCT, MCT1 solute carrier family 16 (monocarboxylate transporter), member 1 C00047211
6583 SLC22A4, OCTN1 solute carrier family 22 (organic cation/zwitterion transporter), member 4 C00047211
9481 SLC25A27, UCP4 solute carrier family 25, member 27 C00047211
6513 SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED solute carrier family 2 (facilitated glucose transporter), member 1 C00047211
6528 SLC5A5, NIS, TDH1 solute carrier family 5 (sodium/iodide cotransporter), member 5 C00047211
8140 SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 C00047211
57223 SMEK2, FLFL2, PP4R3B, PSY2, smk1 SMEK homolog 2, suppressor of mek1 (Dictyostelium) C00047211
6606 SMN1, BCD541, GEMIN1, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMNT, T-BCD541, TDRD16A survival of motor neuron 1, telomeric C00047211
22938 SNW1, Bx42, NCOA-62, PRPF45, Prp45, SKIIP, SKIP SNW domain containing 1 C00047211
8651 SOCS1, CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3 suppressor of cytokine signaling 1 C00047211
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00047211
6654 SOS1, GF1, GGF1, GINGF, HGF, NS4 son of sevenless homolog 1 (Drosophila) C00047211
6742 SSBP1, Mt-SSB, SOSS-B1, SSBP, mtSSB single-stranded DNA binding protein 1, mitochondrial C00047211
6489 ST8SIA1, GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 (EC:2.4.99.8) C00047211
6788 STK3, KRS1, MST2 serine/threonine kinase 3 (EC:2.7.11.1) C00047211
2054 STX2, EPIM, EPM, STX2A, STX2B, STX2C syntaxin 2 C00047211
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00047211
6820 SULT2B1, HSST2 sulfotransferase family, cytosolic, 2B, member 1 (EC:2.8.2.2) C00047211
6827 SUPT4H1, SPT4, SPT4H, SUPT4H suppressor of Ty 4 homolog 1 (S. cerevisiae) C00047211
11346 SYNPO synaptopodin C00047211
6867 TACC1, Ga55 transforming, acidic coiled-coil containing protein 1 C00047211
57252 C00047211
7031 TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 trefoil factor 1 C00047211
7039 TGFA, TFGA transforming growth factor, alpha C00047211
7040 TGFB1, CED, DPD1, LAP, TGFB, TGFbeta transforming growth factor, beta 1 C00047211
7056 THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM thrombomodulin C00047211
7070 THY1, CD90 Thy-1 cell surface antigen C00047211
7082 TJP1, ZO-1 tight junction protein 1 C00047211
51768 TM7SF3 transmembrane 7 superfamily member 3 C00047211
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00047211
7128 TNFAIP3, A20, OTUD7C, TNFA1P2 tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12) C00047211
8797 TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1 tumor necrosis factor receptor superfamily, member 10a C00047211
8795 TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 tumor necrosis factor receptor superfamily, member 10b C00047211
4982 TNFRSF11B, OCIF, OPG, TR1 tumor necrosis factor receptor superfamily, member 11b C00047211
943 TNFRSF8, CD30, D1S166E, Ki-1 tumor necrosis factor receptor superfamily, member 8 C00047211
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00047211
8600 TNFSF11, CD254, ODF, OPGL, OPTB2, RANKL, TRANCE, hRANKL2, sOdf tumor necrosis factor (ligand) superfamily, member 11 C00047211
7134 TNNC1, CMD1Z, CMH13, TN-C, TNC, TNNC troponin C type 1 (slow) C00047211
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00047211
9537 TP53I11, PIG11 tumor protein p53 inducible protein 11 C00047211
8626 TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L tumor protein p63 C00047211
10426 TUBGCP3, 104p, GCP3, Grip104, SPBC98, Spc98, Spc98p tubulin, gamma complex associated protein 3 C00047211
7296 TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR thioredoxin reductase 1 (EC:1.8.1.9) C00047211
7298 TYMS, HST422, TMS, TS thymidylate synthetase (EC:2.1.1.45) C00047211
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00047211
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00047211
7366 UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) C00047211
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00047211
7436 VLDLR, CARMQ1, CHRMQ1, VLDLRCH very low density lipoprotein receptor C00047211
7447 VSNL1, HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1 visinin-like 1 C00047211
10413 YAP1, YAP, YAP2, YAP65, YKI Yes-associated protein 1 C00047211

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (80)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#103780 Alcohol dependence P08172
P14416
P31645
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
%606641 Body mass index; bmi P37231
#300615 Brunner syndrome P21397
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#162800 Cyclic neutropenia P08246
#127750 Dementia, lewy body; dlb P37840
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#614557 Ehlers-danlos syndrome with progressive kyphoscoliosis, myopathy, and hearing loss; edskmh Q9NWM8
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 O75874
P04626
P37231
#610140 Heart-hand syndrome, slovenian type P02545
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603932 Intervertebral disc disease; idd P14780
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
P04637
#612371 Major affective disorder 7; mafd7 P17861
#608516 Major depressive disorder; mdd P08172
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#257220 Niemann-pick disease, type c1; npc1 O15118
#601665 Obesity P32245
P37231
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#275210 Restrictive dermopathy, lethal P02545
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#190300 Tremor, hereditary essential, 1; etm1 P35462
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (80)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00016 Oral cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P00533 (related)
P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
P04637 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
P04637 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
P04637 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
P04637 (related)
P04637 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04626 (related)
P04637 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
P04637 (related)
H00046 Cholangiocarcinoma P04626 (related)
P04637 (related)
P35354 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P14780 (related)
P35354 (related)
H00029 Vulvar cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00044 Cancer of the anal canal P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)

Diseases related to CTD interactions

16 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00047211
D019970 Cocaine-Related Disorders C00047211
D056486 Drug-Induced Liver Injury C00047211
D005909 Glioblastoma C00047211
D006949 Hyperlipidemias C00047211
D007174 Impulse Control Disorders C00047211
D007249 Inflammation C00047211
D007859 Learning Disorders C00047211
D008223 Lymphoma C00047211
D008569 Memory Disorders C00047211
D009135 Muscular Diseases C00047211
D009336 Necrosis C00047211
D009410 Nerve Degeneration C00047211
D009422 Nervous System Diseases C00047211
D011041 Poisoning C00047211
D013226 Status Epilepticus C00047211