PCIDB

Aristolochia argentina Gris.

Species

KNApSAcK Entry

Organism name Aristolochia argentina Gris.
Genus Aristolochia
Family Aristolochiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aristolochia
Linked NCBI taxonomy ID 12947
Linked level genus

Family

Family in NCBI taxonomy Aristolochiaceae
ID 16727

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00025602 External link 512 l-Curine
/ (-)-Curine
/ l-Bebeerine
/ Aristolochine
/ (-)-Bebeerine
/ Aristolochine(C36 alkaloid)
CHEMBL1169627
13 / 6 / 5 No. 10 No. 4

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00025602 0 / 0
Q99700 Ataxin-2 Unclassified protein C00025602 1 / 1
P47898 5-hydroxytryptamine receptor 5A Serotonin receptor C00025602 0 / 0
P42858 Huntingtin Unclassified protein C00025602 1 / 1
O75496 Geminin Unclassified protein C00025602 0 / 0
P41143 Delta-type opioid receptor Opioid receptor C00025602 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00025602 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00025602 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00025602 4 / 3
O43603 Galanin receptor type 2 Galanin receptor C00025602 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00025602 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00025602 0 / 0
P43351 DNA repair protein RAD52 homolog Unclassified protein C00025602 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#143100 Huntington disease; hd P42858
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (5)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)