Species

KNApSAcK Entry

Organism name Streptomyces wedmorensis
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces wedmorensis
Linked NCBI taxonomy ID 43759
Linked level species

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00000916 External link 512 HEP
/ 2-Hydroxyethylphosphonic acid
No. 3559
C00000799 External link 512 Phosphonoacetaldehyde
C003126
No. 3559
C00000788 External link 512 Fosfomycin monophosphate
No. 4697
C00000787 External link 512 Fosfomycin diphosphate
No. 4697
C00000798 External link 512 PEP
/ Phosphoenolpyruvate
/ Phosphoenolpyruvic acid
CHEMBL1235228
2 / 2 / 1 No. 6199
C00000789 External link 512 FM
/ MK 0955
/ Fosfomycin
/ (-)-Phosphonomycin
CHEMBL218627
CHEMBL1757
CHEMBL1555455
CHEMBL1616512
D005578
5 / 4 / 2 1 / 29 No. 7201
C00000801 External link 512 PnPy
/ Phosphonopyruvate
/ Phosphonopyruvic acid
No. 8626

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P83916 Chromobox protein homolog 1 Unclassified protein C00000789 0 / 0
P00734 Prothrombin S1A C00000789 4 / 2
P53582 Methionine aminopeptidase 1 M24A C00000789 0 / 0
P50579 Methionine aminopeptidase 2 M24A C00000789 0 / 0
P12955 Xaa-Pro dipeptidase M24B C00000798 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000789 0 / 0
Q92959 Solute carrier organic anion transporter family member 2A1 Unclassified protein C00000798 1 / 0

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1401 CRP, PTX1 C-reactive protein, pentraxin-related C00000789

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#614441 Hypertrophic osteoarthropathy, primary, autosomal recessive, 2; phoar2 Q92959
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#170100 Prolidase deficiency P12955
#613679 Prothrombin deficiency, congenital P00734
#601367 Stroke, ischemic P00734
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (3)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H01119 Prolidase deficiency (PD) P12955 (related)

Diseases related to CTD interactions

29 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D015746 Abdominal Pain C00000789
D058186 Acute Kidney Injury C00000789
D016470 Bacteremia C00000789
D003428 Cross Infection C00000789
D003550 Cystic Fibrosis C00000789
D003967 Diarrhea C00000789
D015299 Discitis C00000789
D003875 Drug Eruptions C00000789
D056486 Drug-Induced Liver Injury C00000789
D004697 Endocarditis, Bacterial C00000789
D020802 Epidural Abscess C00000789
D004927 Escherichia coli Infections C00000789
D005921 Glomerulonephritis C00000789
D007674 Kidney Diseases C00000789
D007683 Kidney Tubular Necrosis, Acute C00000789
D016920 Meningitis, Bacterial C00000789
D008586 Meningitis, Pneumococcal C00000789
D018410 Pneumonia, Bacterial C00000789
D011183 Postoperative Complications C00000789
D011507 Proteinuria C00000789
D011704 Pyelonephritis C00000789
D052880 Pyomyositis C00000789
D051437 Renal Insufficiency C00000789
D012640 Seizures C00000789
D018805 Sepsis C00000789
D012874 Skin Diseases, Infectious C00000789
D013203 Staphylococcal Infections C00000789
D014552 Urinary Tract Infections C00000789
D014581 Urticaria C00000789