Species

KNApSAcK Entry

Organism name Wurmbea capensis
Genus Wurmbea
Family Colchicaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Wurmbea
Linked NCBI taxonomy ID 217519
Linked level genus

Family

Family in NCBI taxonomy Colchicaceae
ID 41218

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00027741 External link 512 3-Demethylcolchicine
CHEMBL1081
CHEMBL1707904
C007279
21 / 12 / 4 No. 598 No. 4

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00027741 2 / 0
O75496 Geminin Unclassified protein C00027741 0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00027741 2 / 2
Q9UNA4 DNA polymerase iota Enzyme C00027741 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00027741 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00027741 1 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00027741 0 / 0
P68366 Tubulin alpha-4A chain Structural C00027741 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00027741 1 / 0
P04350 Tubulin beta-4A chain Structural C00027741 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00027741 0 / 0
P07437 Tubulin beta chain Structural C00027741 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00027741 1 / 1
P68371 Tubulin beta-4B chain Structural C00027741 0 / 0
Q13509 Tubulin beta-3 chain Structural C00027741 2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein C00027741 0 / 0
Q13885 Tubulin beta-2A chain Structural C00027741 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00027741 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00027741 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00027741 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00027741 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#300018 46,xy sex reversal 2; srxy2 P51843
#300200 Adrenal hypoplasia, congenital; ahc P51843
#114500 Colorectal cancer; crc P84022
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1

KEGG DISEASE (4)

KEGG name UniProt
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)