Lolium perenne
Species
KNApSAcK Entry
| Organism name | Lolium perenne |
|---|---|
| Genus | Lolium |
| Family | Poaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Lolium perenne |
|---|---|
| Linked NCBI taxonomy ID | 4522 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Poaceae |
|---|---|
| ID | 4479 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00000001
|
GA1
/ Gibberellin A1 |
C422660
|
No. 40 | No. 41 |
|
|||
|
C00000008
|
GA8
/ Gibberellin A8 |
No. 40 | No. 41 |
|
||||
|
C00000044
|
GA44
/ Gibberellin A44 |
No. 40 | No. 41 |
|
||||
|
C00000029
|
GA29
/ Gibberellin A29 |
No. 40 | No. 41 |
|
||||
|
C00000020
|
GA20
/ Gibberellin A20 |
No. 40 | No. 41 |
|
||||
|
C00000019
|
GA19
/ Gibberellin A19 |
C120175
|
No. 187 | No. 41 |
|
|||
|
C00000298
|
GA97
/ Gibberellin A97 |
No. 187 | No. 41 |
|
||||
|
C00000053
|
GA53
/ Gibberellin A53 |
No. 187 | No. 41 |
|
||||
|
C00000104
|
5-Hydroxyindole-3-acetic acid
|
CHEMBL395915
|
D006897
|
22 / 32 / 22 | 0 / 8 | No. 1910 | No. 4 |
|
|
C00026507
|
Lolicine A
|
No. 2224 |
|
|||||
|
C00026509
|
Lolitrem N
|
No. 2224 |
|
|||||
|
C00026508
|
Lolicine B
|
No. 2224 |
|
|||||
|
C00001756
|
Perlolyrine
/ Tribulusterine |
CHEMBL501991
|
C055781
|
No. 5379 | No. 4 |
|
Human Protein / Gene in interactions
22 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00000104 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00000104 | 2 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00000104 | 11 / 10 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00000104 | 3 / 2 |
| P02768 | Serum albumin | Secreted protein | C00000104 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000104 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000104 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00000104 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000104 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00000104 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000104 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00000104 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00000104 | 0 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000104 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00000104 | 5 / 2 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00000104 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000104 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000104 | 0 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00000104 | 1 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00000104 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000104 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000104 | 1 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (32)
| OMIM | preferred title | UniProt |
|---|---|---|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #301500 | Fabry disease |
P06280
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (22)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
Diseases related to CTD interactions
8 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000987 | Antisocial Personality Disorder |
C00000104
|
| D001927 | Brain Diseases |
C00000104
|
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00000104
|
| D005391 | Firesetting Behavior |
C00000104
|
| D006973 | Hypertension |
C00000104
|
| D007174 | Impulse Control Disorders |
C00000104
|
| D012640 | Seizures |
C00000104
|
| D013226 | Status Epilepticus |
C00000104
|