Species

KNApSAcK Entry

Organism name Rehmannia glutinosa (Gaertn) Libosch
Genus Rehmannia
Family Scrophulariaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rehmannia
Linked NCBI taxonomy ID 99299
Linked level genus

Family

Family in NCBI taxonomy
ID

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029547 External link 512 5-Hydroxymethylfuraldehyde
/ 5-Hydroxymethyl-2-furfural
/ 5-Hydroxymethyl-2-furaldehyde
/ 5-(Hydroxymethyl)-2-furaldehyde
CHEMBL185885
C008046
4 / 3 / 3 2 / 5 No. 6025

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P16473 Thyrotropin receptor Glycohormone receptor C00029547 3 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00029547 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00029547 0 / 1
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00029547 0 / 0

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
6817 SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1) C00029547
6799 SULT1A2, HAST4, P-PST, ST1A2, STP2, TSPST2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 (EC:2.8.2.1) C00029547

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473

KEGG DISEASE (3)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D058739 Aberrant Crypt Foci C00029547
D018248 Adenoma, Liver Cell C00029547
D008113 Liver Neoplasms C00029547
D010212 Papilloma C00029547
D012878 Skin Neoplasms C00029547