Species

KNApSAcK Entry

Organism name Cedrela sinensis
Genus Cedrela
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Toona sinensis
Linked NCBI taxonomy ID 443222
Linked level species

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00031038 External link 512 Piscidinol A
/ (-)-Piscidinol A
CHEMBL1508930
12 / 23 / 20 No. 119 No. 51
C00041290 External link 512 7-Deacetoxy-7alpha,11alpha-dihydroxygedunin
/ (+)-7-Deacetoxy-7alpha,11alpha-dihydroxygedunin
CHEMBL463400
CHEMBL513222
No. 204 No. 51
C00041234 External link 512 11beta-Hydroxygedunin
/ (+)-11beta-Hydroxygedunin
CHEMBL462806
CHEMBL480303
No. 204 No. 51
C00041291 External link 512 7-Deacetoxy-7alpha,11beta-Dihydroxygedunin
CHEMBL463400
CHEMBL513222
No. 204 No. 51
C00041233 External link 512 11alpha-Hydroxygedunin
/ (+)-11alpha-Hydroxygedunin
CHEMBL462806
CHEMBL480303
No. 204 No. 51
C00029846 External link 512 Bourjotinolone A
No. 264 No. 51
C00030484 External link 512 Hispidol B
No. 264 No. 51
C00029764 External link 512 Azadirone
CHEMBL338847
CHEMBL1215753
No. 453
C00030427 External link 512 Grandifoliolenone
CHEMBL1356418
1 / 4 / 3 No. 1247
C00031287 External link 512 Sapelin E acetate
No. 1247

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10636 Microtubule-associated protein tau Unclassified protein C00030427 C00031038 4 / 3
O75496 Geminin Unclassified protein C00031038 0 / 0
P06746 DNA polymerase beta Enzyme C00031038 0 / 0
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00031038 1 / 4
P42858 Huntingtin Unclassified protein C00031038 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00031038 2 / 0
Q99700 Ataxin-2 Unclassified protein C00031038 1 / 1
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00031038 7 / 3
Q16637 Survival motor neuron protein Unclassified protein C00031038 4 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00031038 0 / 0
O00255 Menin Unclassified protein C00031038 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00031038 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (23)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#208900 Ataxia-telangiectasia; at Q13315
#114500 Colorectal cancer; crc P84022
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#143100 Huntington disease; hd P42858
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (20)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)