PCIDB

Heracleum mantegazzianium

Species

KNApSAcK Entry

Organism name Heracleum mantegazzianium
Genus Heracleum
Family Apiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Heracleum
Linked NCBI taxonomy ID 40917
Linked level genus

Family

Family in NCBI taxonomy Apiaceae
ID 4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00031604 External link 512 Apterin
CHEMBL1335374
4 / 9 / 5 No. 399 No. 25
C00030987 External link 512 Phellopterin
CHEMBL452751
C104601
7 / 18 / 10 No. 606 No. 25

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00030987 C00031604 7 / 3
P56817 Beta-secretase 1 A1A C00030987 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00031604 0 / 0
P11413 Glucose-6-phosphate 1-dehydrogenase Enzyme C00030987 1 / 2
P37840 Alpha-synuclein Unclassified protein C00030987 4 / 2
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00030987 1 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00031604 2 / 2
P10636 Microtubule-associated protein tau Unclassified protein C00030987 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00031604 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00030987 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (20)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300908 Anemia, nonspherocytic hemolytic, due to g6pd deficiency P11413
#127750 Dementia, lewy body; dlb P37840
#119900 Digital clubbing, isolated congenital P15428
#600274 Frontotemporal dementia; ftd P10636
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (12)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00101 Other phagocyte defects P11413 (related)
H00668 Anemia due to disorders of glutathione metabolism P11413 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)