Species

KNApSAcK Entry

Organism name Akania lucens
Genus Akania
Family Akaniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Akania
Linked NCBI taxonomy ID 19374
Linked level genus

Family

Family in NCBI taxonomy Akaniaceae
ID 19373

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00035253 External link 512 Betulonic acid
/ (+)-Betulonic acid
CHEMBL431525
CHEMBL1329485
8 / 15 / 11 No. 23 No. 51

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00035253 4 / 1
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor C00035253 0 / 0
P02545 Prelamin-A/C Unclassified protein C00035253 11 / 10
P11387 DNA topoisomerase 1 Isomerase C00035253 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00035253 0 / 0
O75496 Geminin Unclassified protein C00035253 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00035253 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00035253 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (11)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)