PCIDB

KNApSAcK Metabolite C00035253

Metabolite

KNApSAcK Entry

id C00035253
Name Betulonic acid / (+)-Betulonic acid
CAS RN 4481-62-3
Standard InChI InChI=1S/C30H46O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-22,24H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,24+,27-,28+,29+,30-/m0/s1
Standard InChI (Main Layer) InChI=1S/C30H46O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-22,24H,1,8-17H2,2-7H3,(H,32,33)

Cluster

Phytochemical cluster No. 51
KCF-S cluster No. 23

Link

ChEMBL

By standard InChI CHEMBL431525
By standard InChI Main Layer CHEMBL431525 CHEMBL1329485

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

8 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein CHEMBL1329485 CHEMBL1613842 (1)
4 / 2
Q8TDU6 G-protein coupled bile acid receptor 1 Steroid-like ligand receptor CHEMBL431525 CHEMBL1041788 (1) CHEMBL1041789 (1)
0 / 0
P02545 Prelamin-A/C Unclassified protein CHEMBL1329485 CHEMBL1614544 (1)
11 / 10
P11387 DNA topoisomerase 1 Isomerase CHEMBL431525 CHEMBL1108448 (1)
0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase CHEMBL431525 CHEMBL1108449 (1)
0 / 0
O75496 Geminin Unclassified protein CHEMBL1329485 CHEMBL2114843 (1)
0 / 0
Q96RI1 Bile acid receptor NR1H4 CHEMBL431525 CHEMBL1041790 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1329485 CHEMBL1794483 (1)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (11)

KEGG disease name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
Q16637 (related)