Species

KNApSAcK Entry

Organism name Saccharopolyspora spinosa
Genus Saccharopolyspora
Family Pseudonocardiaceae
Kingdom

NCBI taxonomy

Entry

Linked NCBI taxonomy name Saccharopolyspora spinosa
Linked NCBI taxonomy ID 60894
Linked level species

Family

Family in NCBI taxonomy Pseudonocardiaceae
ID 2070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00041878 External link 512 Spinosyn A
/ (-)-Spinosyn A
CHEMBL501411
CHEMBL1874717
7 / 11 / 11 No. 5644
C00041879 External link 512 Spinosyn B
No. 5644

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00041878 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00041878 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00041878 2 / 3
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00041878 5 / 3
P03372 Estrogen receptor NR3A1 C00041878 1 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00041878 0 / 0
P10275 Androgen receptor NR3C4 C00041878 3 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#615363 Estrogen resistance; estrr P03372
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (11)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)