Azadirachta excelsa
Species
KNApSAcK Entry
| Organism name | Azadirachta excelsa |
|---|---|
| Genus | Azadirachta |
| Family | Meliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Azadirachta |
|---|---|
| Linked NCBI taxonomy ID | 124942 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Meliaceae |
|---|---|
| ID | 43707 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00042268
|
Azadirachtol
|
No. 453 |
|
|||||
|
C00042265
|
Azadirachtin O
/ (-)-Azadirachtin O |
CHEMBL526884
|
No. 487 | No. 51 |
|
|||
|
C00042264
|
Azadirachtin M
/ (-)-Azadirachtin M |
No. 487 | No. 51 |
|
||||
|
C00042266
|
Azadirachtin P
/ (-)-Azadirachtin P |
CHEMBL510520
|
No. 487 | No. 51 |
|
|||
|
C00042041
|
11alpha-Azadirachtin H
|
CHEMBL504820
|
No. 487 | No. 51 |
|
|||
|
C00042267
|
Azadirachtin Q
/ (-)-Azadirachtin Q |
CHEMBL502955
|
No. 487 | No. 51 |
|
|||
|
C00048939
|
2,3-Dihydronimbolide
/ (+)-2,3-Dihydronimbolide |
CHEMBL1991257
|
No. 2762 |
|
||||
|
C00048947
|
3-Deoxymethylnimbidate
/ (+)-3-Deoxymethylnimbidate |
No. 2762 |
|
|||||
|
C00049007
|
Nimbolide
|
CHEMBL426690
CHEMBL1968854 |
C042198
|
20 / 1 | No. 2762 |
|
Human Protein / Gene in interactions
20 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 317 | APAF1, APAF-1, CED4 | apoptotic peptidase activating factor 1 |
C00049007
|
| 572 | BAD, BBC2, BCL2L8 | BCL2-associated agonist of cell death |
C00049007
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00049007
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00049007
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00049007
|
| 637 | BID, FP497 | BH3 interacting domain death agonist |
C00049007
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00049007
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00049007
|
| 839 | CASP6, MCH2 | caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59) |
C00049007
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00049007
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00049007
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00049007
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00049007
|
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00049007
|
| 3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00049007
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00049007
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00049007
|
| 5111 | PCNA | proliferating cell nuclear antigen |
C00049007
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00049007
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00049007
|