Species

KNApSAcK Entry

Organism name Streptomyces argillaceus ATCC12956
Genus Streptomyces
Family Streptomycetaceae
Kingdom Bacteria

NCBI taxonomy

Entry

Linked NCBI taxonomy name Streptomyces
Linked NCBI taxonomy ID 1883
Linked level genus

Family

Family in NCBI taxonomy Streptomycetaceae
ID 2062

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Bacteria
ID 2

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00049230 External link 512 Mithramycin
CHEMBL413720
CHEMBL255884
CHEMBL535101
CHEMBL1881779
CHEMBL2355736
D008926
4 / 2 / 0 11 / 2 No. 906

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P39748 Flap endonuclease 1 Enzyme C00049230 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00049230 2 / 0
Q9UNA4 DNA polymerase iota Enzyme C00049230 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00049230 0 / 0

11 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
558 AXL, JTK11, UFO AXL receptor tyrosine kinase (EC:2.7.10.1) C00049230
999 CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO cadherin 1, type 1, E-cadherin (epithelial) C00049230
54541 DDIT4, Dig2, REDD-1, REDD1 DNA-damage-inducible transcript 4 C00049230
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00049230
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00049230
3458 IFNG, IFG, IFI interferon, gamma C00049230
4128 MAOA, MAO-A monoamine oxidase A (EC:1.4.3.4) C00049230
5320 PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4) C00049230
5444 PON1, ESA, MVCD5, PON paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) C00049230
6667 SP1 Sp1 transcription factor C00049230
8743 TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL tumor necrosis factor (ligand) superfamily, member 10 C00049230

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D009202 Cardiomyopathies C00049230
D012208 Rhabdomyosarcoma C00049230