PCIDB

Cryptocarya pyriformis

Species

KNApSAcK Entry

Organism name Cryptocarya pyriformis
Genus Cryptocarya
Family Lauraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cryptocarya
Linked NCBI taxonomy ID 22027
Linked level genus

Family

Family in NCBI taxonomy Lauraceae
ID 3433

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00000104 External link 512 5-Hydroxyindole-3-acetic acid
CHEMBL395915
D006897
22 / 32 / 22 0 / 8 No. 1910 No. 4

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000104 1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00000104 2 / 0
P02545 Prelamin-A/C Unclassified protein C00000104 11 / 10
P16473 Thyrotropin receptor Glycohormone receptor C00000104 3 / 2
P02768 Serum albumin Secreted protein C00000104 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000104 0 / 1
P11473 Vitamin D3 receptor NR1I1 C00000104 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00000104 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000104 2 / 0
O75496 Geminin Unclassified protein C00000104 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000104 0 / 0
P06280 Alpha-galactosidase A Enzyme C00000104 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00000104 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000104 2 / 2
Q01453 Peripheral myelin protein 22 Unclassified protein C00000104 5 / 2
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00000104 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000104 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000104 0 / 1
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00000104 1 / 0
Q99549 M-phase phosphoprotein 8 Unclassified protein C00000104 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00000104 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000104 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (32)

OMIM preferred title UniProt
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#118300 Charcot-marie-tooth disease and deafness Q01453
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#118220 Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a Q01453
#114500 Colorectal cancer; crc P84022
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#301500 Fabry disease P06280
#137800 Glioma susceptibility 1; glm1 O75874
#139393 Guillain-barre syndrome, familial; gbs Q01453
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#145900 Hypertrophic neuropathy of dejerine-sottas Q01453
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#162500 Neuropathy, hereditary, with liability to pressure palsies; hnpp Q01453
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (22)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
Q01453 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H01296 Hereditary neuropathy with liability to pressure palsies (HNPP) Q01453 (related)

Diseases related to CTD interactions

8 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000987 Antisocial Personality Disorder C00000104
D001927 Brain Diseases C00000104
D064420 Drug-Related Side Effects and Adverse Reactions C00000104
D005391 Firesetting Behavior C00000104
D006973 Hypertension C00000104
D007174 Impulse Control Disorders C00000104
D012640 Seizures C00000104
D013226 Status Epilepticus C00000104