Symplocos spicata
Species
KNApSAcK Entry
| Organism name | Symplocos spicata |
|---|---|
| Genus | Symplocos |
| Family | Symplocaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Symplocos |
|---|---|
| Linked NCBI taxonomy ID | 55372 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Symplocaceae |
|---|---|
| ID | 20019 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (2)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005510
|
Rhamnetin 3-galactosyl-(1->4)-galactoside
|
CHEMBL539431
|
No. 1 | No. 15 |
|
|||
|
C00000990
|
Phloridzin
/ Phloretin 2'-glucoside |
CHEMBL45266
CHEMBL245067 CHEMBL1320052 CHEMBL1524370 CHEMBL2096900 |
D010695
|
16 / 15 / 14 | 3 / 7 | No. 36 | No. 13 |
|
Human Protein / Gene in interactions
16 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P13866 | Sodium/glucose cotransporter 1 | Glucose | C00000990 | 1 / 1 |
| P31639 | Sodium/glucose cotransporter 2 | Glucose | C00000990 | 1 / 1 |
| O00337 | Sodium/nucleoside cotransporter 1 | Unclassified protein | C00000990 | 0 / 0 |
| Q9HAS3 | Solute carrier family 28 member 3 | Unclassified protein | C00000990 | 0 / 0 |
| Q99808 | Equilibrative nucleoside transporter 1 | Nucleoside uniporter | C00000990 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00000990 | 3 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00000990 | 0 / 1 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00000990 | 0 / 0 |
| Q9NY91 | Low affinity sodium-glucose cotransporter | Unclassified protein | C00000990 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00000990 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00000990 | 2 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00000990 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000990 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000990 | 4 / 3 |
| O43868 | Sodium/nucleoside cotransporter 2 | Unclassified protein | C00000990 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000990 | 0 / 0 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00000990
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00000990
|
| 6523 | SLC5A1, D22S675, NAGT, SGLT1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
C00000990
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (15)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #606824 | Glucose/galactose malabsorption; ggm |
P13866
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #233100 | Renal glucosuria; glys1 |
P31639
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01261 | Congenital glucose-galactose malabsorption (GGM) |
P13866
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01126 | Familial renal glucosuria (FRG) |
P31639
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
Diseases related to CTD interactions
7 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D002418 | Cattle Diseases |
C00000990
|
| D003921 | Diabetes Mellitus, Experimental |
C00000990
|
| D006029 | Glycosuria |
C00000990
|
| D006943 | Hyperglycemia |
C00000990
|
| D007003 | Hypoglycemia |
C00000990
|
| D007662 | Ketosis |
C00000990
|
| D015431 | Weight Loss |
C00000990
|