Helichrysum herbaceum
Species
KNApSAcK Entry
| Organism name | Helichrysum herbaceum |
|---|---|
| Genus | Helichrysum |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Helichrysum |
|---|---|
| Linked NCBI taxonomy ID | 59430 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003830
|
8-Hydroxy-5,6,7-trimethoxyflavone
|
No. 3 | No. 15 |
|
||||
|
C00003829
|
5,8-Dihydroxy-6,7-dimethoxyflavone
/ 5,8-Dihydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00003832
|
5,6,7,8-Tetramethoxyflavone
/ 5,6,7,8-Tetramethoxy-2-phenyl-4H-1-benzopyran-4-one |
No. 3 | No. 15 |
|
||||
|
C00003882
|
7-Hydroxy-5,6,8,4'-tetramethoxyflavone
|
No. 8 | No. 15 |
|
||||
|
C00001028
|
5,7-Dimethoxyflavone
/ chrysin 5,7-dimethyl ether |
CHEMBL275391
|
C060298
|
14 / 13 / 13 | 2 / 3 | No. 35 | No. 15 |
|
Human Protein / Gene in interactions
14 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001028 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001028 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00001028 | 4 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00001028 | 0 / 0 |
| P51843 | Nuclear receptor subfamily 0 group B member 1 | Nuclear hormone receptor subfamily 0 group B member 1 | C00001028 | 2 / 2 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001028 | 2 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001028 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001028 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001028 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001028 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001028 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001028 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001028 | 1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001028 | 1 / 1 |
2 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001028
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001028
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300018 | 46,xy sex reversal 2; srxy2 |
P51843
|
| #300200 | Adrenal hypoplasia, congenital; ahc |
P51843
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
KEGG DISEASE (13)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|
| H00552 | Glycerol kinase deficiency (GKD) |
P51843
(related)
|
| H00607 | 46,XY disorders of sex development (Disorders of gonadal development) |
P51843
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|