Species

KNApSAcK Entry

Organism name Cirsium lineare
Genus Cirsium
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cirsium lineare
Linked NCBI taxonomy ID 196725
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004416 External link 512 6-Hydroxyluteolin 6,7,3'-trimethyl ether 4'-glucoside
CHEMBL487414
CHEMBL476097
No. 2 No. 15
C00004409 External link 512 6-Hydroxyluteolin 6,7-dimethyl ether 4'-glucoside
CHEMBL487212
CHEMBL514993
No. 2 No. 15
C00001033 External link 512 Cirsiliol
CHEMBL72637
C039824
2 / 4 / 4 2 / 0 No. 3 No. 15
C00013595 External link 512 Eupatrin
/ Anisomelin
/ Fastigenin
/ Cirsilineol
/ 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone
CHEMBL487213
C057618
No. 3 No. 15

Human Protein / Gene in interactions

2 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00001033 0 / 0
Q16678 Cytochrome P450 1B1 Cytochrome P450 1B1 C00001033 4 / 4

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001033
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00001033

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#137750 Glaucoma 1, open angle, a; glc1a Q16678
#231300 Glaucoma 3, primary congenital, a; glc3a Q16678
#137760 Glaucoma, primary open angle; poag Q16678
#604229 Peters anomaly Q16678

KEGG DISEASE (4)

KEGG name UniProt
H00612 Primary open angle glaucoma Q16678 (related)
H01075 Peters anomaly Q16678 (related)
H01159 Anterior segment dysgenesis (ASD) Q16678 (related)
H01203 Primary congenital glaucoma (PCG) Q16678 (related)