Eupatorium altissimum
Species
KNApSAcK Entry
| Organism name | Eupatorium altissimum |
|---|---|
| Genus | Eupatorium |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Eupatorium altissimum |
|---|---|
| Linked NCBI taxonomy ID | 102769 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (6)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001036
|
Diosmetin
/ 4'-Methylluteolin / 5,7,3'-Trihydroxy-4'-methoxyflavone |
CHEMBL90568
|
C039602
|
11 / 12 / 8 | 5 / 0 | No. 3 | No. 15 |
|
|
C00004593
|
6-Methoxykaempferol
/ 3,5,7,4'-Tetrahydroxy-6-methoxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one |
CHEMBL462898
|
No. 3 | No. 15 |
|
|||
|
C00003894
|
Eupatorin
/ 3',5-Dihydroxy-4',6,7-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL487402
|
C103110
|
5 / 5 / 4 | 5 / 0 | No. 3 | No. 15 |
|
|
C00004596
|
6-Methoxykaempferol 3-methyl ether
/ 5,7,4'-Trihydroxy-3,6-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL351607
|
C014868
|
No. 3 | No. 15 |
|
||
|
C00003898
|
5-Hydroxy-6,7,3',4'-tetramethoxyflavone
/ 6-Hydroxyluteolin 6,7,3',4'-tetramethyl ether / 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL226508
|
C045324
|
No. 8 | No. 15 |
|
||
|
C00002111
|
Rinderine
|
CHEMBL445876
CHEMBL471483 CHEMBL450265 |
No. 308 | No. 2 |
|
Human Protein / Gene in interactions
14 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00001036 C00003894 | 0 / 0 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00001036 C00003894 | 4 / 4 |
| Q96GD4 | Aurora kinase B | Aur | C00003894 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00001036 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001036 | 5 / 3 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001036 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00001036 | 0 / 0 |
| O14965 | Aurora kinase A | Aur | C00003894 | 0 / 0 |
| P35968 | Vascular endothelial growth factor receptor 2 | Vegfr | C00003894 | 1 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001036 | 0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001036 | 2 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001036 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001036 | 0 / 0 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00001036 | 0 / 0 |
7 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001036
C00003894
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001036
C00003894
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00001036
C00003894
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001036
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00001036
|
| 1557 | CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 | cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00003894
|
| 1565 | CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 | cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) |
C00003894
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #602089 | Hemangioma, capillary infantile |
P35968
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #601665 | Obesity |
P37231
|
| #604229 | Peters anomaly |
Q16678
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|