Species

KNApSAcK Entry

Organism name Anadenanthera peregrina
Genus Anadenanthera
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Anadenanthera peregrina
Linked NCBI taxonomy ID 148672
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001055 External link 512 Isoorientin
/ Homoorientin
/ Lespecapitioside
/ Luteolin 6-C-beta-D-glucopyranoside
/ 2-(3,4-Dihydroxyphenyl)-6-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
CHEMBL239559
CHEMBL1302308
C057912
23 / 14 / 17 0 / 1 No. 22 No. 15
C00001059 External link 512 Isovitexin
/ Saponaretin
/ Homovitexin
/ 6-C-beta-D-Glucopyranosylapigenin
/ 6-beta-D-Glucopyranosyl-4',5,7-trihydroxyflavone
/ 6-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL465360
CHEMBL1601394
C049772
28 / 20 / 19 No. 22 No. 15
C00020638 External link 512 Leucopelargonidin
/ 3,4,5,7,4'-Flavanpentol
No. 52 No. 14

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001055 C00001059 0 / 0
P06746 DNA polymerase beta Enzyme C00001055 C00001059 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001055 C00001059 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00001055 C00001059 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00001055 C00001059 1 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001055 C00001059 2 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001055 C00001059 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001055 C00001059 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00001055 C00001059 1 / 4
Q9Y253 DNA polymerase eta Enzyme C00001055 C00001059 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00001055 C00001059 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001055 C00001059 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001055 C00001059 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001055 C00001059 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001055 C00001059 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001055 C00001059 1 / 1
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001055 C00001059 1 / 2
O00255 Menin Unclassified protein C00001055 C00001059 2 / 5
Q9UBT6 DNA polymerase kappa Enzyme C00001055 C00001059 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001055 C00001059 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001055 C00001059 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001059 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001059 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001059 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001055 4 / 3
P30989 Neurotensin receptor type 1 Neurotensin receptor C00001059 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001059 7 / 3
P17405 Sphingomyelin phosphodiesterase Enzyme C00001059 2 / 2
Q9H0H5 Rac GTPase-activating protein 1 Unclassified protein C00001055 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001059 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (24)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (22)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
Q03164 (related)
Q03164 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008104 Liver Cirrhosis, Alcoholic C00001055