Species

KNApSAcK Entry

Organism name Haplopappus deserticola
Genus Haplopappus
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Haplopappus
Linked NCBI taxonomy ID 71051
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001062 External link 512 Isokaempferide
/ Kaempferol 3-methyl ether
/ 5,7,4'-trihydroxy-3-methoxyflavone
CHEMBL165064
19 / 4 / 3 No. 3 No. 15
C00004615 External link 512 3,8-Dimethylherbacetin
/ Herbacetin 3,8-dimethyl ether
/ 5,7,4'-Trihydroxy-3,8-dimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,8-dimethoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00004735 External link 512 Gossypetin 3,8,3'-trimethyl ether
/ 5,7,4'-Trihydroxy-3,8,3'-trimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL1985918
No. 3 No. 15
C00004621 External link 512 3,8,4'-Trimethylherbacetin
/ Herbacetin 3,8,4'-trimethyl ether
/ 5,7-Dihydroxy-3,8,4'-trimethoxyflavone
/ 5,7-dDihydroxy-3,8-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL349895
No. 3 No. 15
C00038177 External link 512 18-Acetoxy-cis-cleroda-3,13E-dien-15-oic acid
No. 221
C00038993 External link 512 Deserticolic acid
/ (-)-Deserticolic acid
No. 221
C00022523 External link 512 ent-Copaiferolic acid
/ ent-18-Hydroxy-8(17),13-labdadien-15-oic acid
No. 228
C00023395 External link 512 Methyl haplodesertoate
No. 4809

Human Protein / Gene in interactions

19 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001062 1 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00001062 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001062 0 / 0
P06746 DNA polymerase beta Enzyme C00001062 0 / 0
P39748 Flap endonuclease 1 Enzyme C00001062 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00001062 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00001062 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001062 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001062 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00001062 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00001062 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001062 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00001062 0 / 0
Q07817 Bcl-2-like protein 1 Other cytosolic protein C00001062 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00001062 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001062 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00001062 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001062 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00001062 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc Q14191
#608902 Drug metabolism, poor, cyp2d6-related P10635
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (3)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00296 Defects in RecQ helicases Q14191 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)