Species

KNApSAcK Entry

Organism name Cheilanthes argentea
Genus Cheilanthes
Family Pteridaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Cheilanthes argentea
Linked NCBI taxonomy ID 238825
Linked level species

Family

Family in NCBI taxonomy Pteridaceae
ID 13819

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Euphyllophyta
ID 78536

Metabolite list (19)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001075 External link 512 Nevadensin
CHEMBL312073
C023982
1 / 0 / 0 No. 3 No. 15
C00001104 External link 512 Tambulin
CHEMBL478811
No. 3 No. 15
C00003837 External link 512 Cirsimaritin
CHEMBL348436
C007072
13 / 18 / 14 No. 3 No. 15
C00003876 External link 512 Desmethoxysudachitin
/ 5,7,4'-Trihydroxy-6,8-dimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL476120
C078367
No. 3 No. 15
C00003879 External link 512 Xanthomicrol
/ 5-Hydroxy-2-(4-hydroxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL476121
C462036
No. 3 No. 15
C00003880 External link 512 Pedunculin
No. 3 No. 15
C00004606 External link 512 Mikanin
/ 3,5-Dihydroxy-4',6,7-trimethoxyflavone
/ 3,5-Dihydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL554063
No. 3 No. 15
C00004612 External link 512 Pollenitin
/ 7-O-Methylherbacetin
/ 3,4',5,8-Tetrahydroxy-7-methoxyflavone
/ 3,5,8-Trihydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00004616 External link 512 Herbacetin 7,8-dimethyl ether
/ 3,5,4'-Trihydroxy-7,8-dimethoxyflavone
/ 3,5-Dihydroxy-2-(4-hydroxyphenyl)-7,8-dimethoxy-4H-1-benzopyran-4-one
No. 3 No. 15
C00004669 External link 512 3,5,4'-Trihydroxy-6,7,8-trimethoxyflavone
No. 8 No. 15
C00008252 External link 512 5,4'-Dihydroxy-6,7-dimethoxyflavanone
CHEMBL210692
CHEMBL502359
1 / 0 / 0 No. 25 No. 14
C00008254 External link 512 5,4'-Dihydroxy-7,8-dimethoxyflavanone
No. 25 No. 14
C00008256 External link 512 5,6-Dihydroxy-7,8,4'-trimethoxyflavanone
No. 77 No. 14
C00008255 External link 512 5-Hydroxy-7,8,4'-trimethoxyflavanone
No. 77 No. 14
C00008253 External link 512 5-Hydroxy-6,7,4'-trimethoxyflavanone
No. 77 No. 14
C00008257 External link 512 5,4'-Dihydroxy-6,7,8-trimethoxyflavanone
No. 77 No. 14
C00008276 External link 512 5-Hydroxy-6,7,8,4'-tetramethoxyflavanone
No. 77 No. 14
C00008277 External link 512 4'-Hydroxy-5,6,7-trimethoxyflavanone
CHEMBL485055
No. 77 No. 14
C00008349 External link 512 Eriodictyol 7,3',4'-trimethyl ether
No. 77 No. 14

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00003837 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003837 0 / 3
P33765 Adenosine receptor A3 Adenosine receptor C00003837 0 / 0
P06746 DNA polymerase beta Enzyme C00003837 0 / 0
P04062 Glucosylceramidase Enzyme C00003837 6 / 4
P15559 NAD(P)H dehydrogenase [quinone] 1 Enzyme C00001075 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00003837 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003837 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00003837 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00003837 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003837 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00003837 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003837 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00003837 0 / 0
P59538 Taste receptor type 2 member 31 Taste receptor (taste family GPCR) C00008252 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (14)

KEGG name UniProt
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)