Species

KNApSAcK Entry

Organism name Achillea multifida
Genus Achillea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Achillea multifida
Linked NCBI taxonomy ID 282751
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001096 External link 512 Santin
CHEMBL161957
C104803
9 / 7 / 5 No. 3 No. 15
C00004694 External link 512 Centaureidin
/ Desmethoxycentaureidine
/ Quercetagetin 3,4',6-trimethyl ether
/ 5,7,3'-Trihydroxy-3,6,4'-trimethoxyflavone
/ 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one
CHEMBL77552
C083161
24 / 14 / 6 No. 3 No. 15

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00001096 C00004694 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001096 C00004694 1 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001096 C00004694 0 / 0
O75496 Geminin Unclassified protein C00001096 C00004694 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004694 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00004694 2 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001096 1 / 1
P14618 Pyruvate kinase PKM Enzyme C00001096 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00004694 1 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00001096 0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00004694 2 / 2
P10636 Microtubule-associated protein tau Unclassified protein C00001096 4 / 3
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001096 0 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00004694 0 / 0
P39748 Flap endonuclease 1 Enzyme C00004694 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004694 1 / 0
P04350 Tubulin beta-4A chain Structural C00004694 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004694 0 / 0
P07437 Tubulin beta chain Structural C00004694 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004694 1 / 1
P68371 Tubulin beta-4B chain Structural C00004694 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004694 2 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00004694 0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein C00004694 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004694 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004694 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004694 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004694 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00004694 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#300018 46,xy sex reversal 2; srxy2 P51843
#300200 Adrenal hypoplasia, congenital; ahc P51843
#114500 Colorectal cancer; crc P84022
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (10)

KEGG name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00192 Xanthinuria P47989 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)