PCIDB

KNApSAcK Metabolite C00001096

Metabolite

KNApSAcK Entry

id C00001096
Name Santin
CAS RN 27782-63-4
Standard InChI InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)16-18(24-3)15(21)13-12(25-16)8-11(19)17(23-2)14(13)20/h4-8,19-20H,1-3H3
Standard InChI (Main Layer) InChI=1S/C18H16O7/c1-22-10-6-4-9(5-7-10)16-18(24-3)15(21)13-12(25-16)8-11(19)17(23-2)14(13)20/h4-8,19-20H,1-3H3

Cluster

Phytochemical cluster No. 15
KCF-S cluster No. 3

Link

ChEMBL

By standard InChI CHEMBL161957
By standard InChI Main Layer CHEMBL161957

KEGG

By LinkDB C10180

CTD

By CAS RN C104803

Species

Summary

Plant class

class name count
asterids 18
rosids 5
eudicotyledons 2

Family

family name count
Asteraceae 16
Betulaceae 2
Cistaceae 1
Crassulaceae 1
Didiereaceae 1
Plantaginaceae 1
Rutaceae 1
Juglandaceae 1
Lamiaceae 1

List (25)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Achillea atrata 282721 Asteraceae asterids Viridiplantae
Achillea latiloba 359926 Asteraceae asterids Viridiplantae
Achillea multifida 282751 Asteraceae asterids Viridiplantae
Aeonium spp. 22994 Crassulaceae eudicotyledons Viridiplantae
Ageratina espinosara 102749 Asteraceae asterids Viridiplantae
Ajania fruticulosa 99024 Asteraceae asterids Viridiplantae
Alluaudia sp. 3585 Didiereaceae eudicotyledons Viridiplantae
Alnus glutinosa 3517 Betulaceae rosids Viridiplantae
Anthemis tinctoria 99028 Asteraceae asterids Viridiplantae
Artemisia barrelieri 72335 Asteraceae asterids Viridiplantae
Betula ermanii 216992 Betulaceae rosids Viridiplantae
Brickellia eupatorioides 102754 Asteraceae asterids Viridiplantae
Cistus albanicus 566271 Cistaceae rosids Viridiplantae
Digitalis orientalis 4163 Plantaginaceae asterids Viridiplantae
Drummondita hassellii 282608 Rutaceae rosids Viridiplantae
Eupatorium cannabinum 102770 Asteraceae asterids Viridiplantae
Grindelia glutinosa 1114736 Asteraceae asterids Viridiplantae
Grindelia squarrosa 1114761 Asteraceae asterids Viridiplantae
Grindelia tarapacana 1114766 Asteraceae asterids Viridiplantae
Juglans cinerea 91214 Juglandaceae rosids Viridiplantae
Perityle lemmonii 176560 Asteraceae asterids Viridiplantae
Salvia pedicellata 21880 Lamiaceae asterids Viridiplantae
Stevia berlandieri 558448 Asteraceae asterids Viridiplantae
Tanacetum microphyllum 127997 Asteraceae asterids Viridiplantae
Tanacetum parthenium 127999 Asteraceae asterids Viridiplantae

Human Protein / Gene in interaction

9 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL161957 CHEMBL1738312 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL161957 CHEMBL2114784 (1)
1 / 1
P14618 Pyruvate kinase PKM Enzyme CHEMBL161957 CHEMBL1613996 (1) CHEMBL1614428 (1)
0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase CHEMBL161957 CHEMBL973963 (1)
1 / 1
O75496 Geminin Unclassified protein CHEMBL161957 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL161957 CHEMBL2114788 (1)
0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme CHEMBL161957 CHEMBL1963863 (1)
0 / 0
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL161957 CHEMBL1614421 (1)
4 / 3
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL161957 CHEMBL2354311 (1)
1 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278300 Xanthinuria, type i P47989

KEGG DISEASE (5)

KEGG disease name UniProt
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00192 Xanthinuria P47989 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)