Species

KNApSAcK Entry

Organism name Artemisia barrelieri
Genus Artemisia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Artemisia barrelieri
Linked NCBI taxonomy ID 72335
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001096 External link 512 Santin
CHEMBL161957
C104803
9 / 7 / 5 No. 3 No. 15
C00004694 External link 512 Centaureidin
/ Desmethoxycentaureidine
/ Quercetagetin 3,4',6-trimethyl ether
/ 5,7,3'-Trihydroxy-3,6,4'-trimethoxyflavone
/ 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one
CHEMBL77552
C083161
24 / 14 / 6 No. 3 No. 15
C00004680 External link 512 Patuletin
/ 6-Methoxyquercetin
/ 3,5,7,3',4'-Pentahydroxy-6-methoxyflavone
/ 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6-methoxy-4H-1-benzopyran-4-one
CHEMBL465155
C079162
No. 3 No. 15
C00003865 External link 512 7-O-Methylluteolin
/ Luteolin 7-methyl ether
/ 5,3',4'-Trihydroxy-7-methoxyflavone
/ 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
CHEMBL183745
C051414
1 / 1 / 2 No. 3 No. 15
C00003393 External link 512 Barrelin
/ Vulgarin
/ Tauremizin
/ Judaicin (sesquiterpene)
CHEMBL1422618
5 / 14 / 40 No. 755 No. 38

Human Protein / Gene in interactions

34 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00001096 C00003393 C00004694 0 / 0
Q99700 Ataxin-2 Unclassified protein C00001096 C00004694 1 / 1
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00001096 C00004694 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00001096 C00004694 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00003393 7 / 37
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001096 1 / 1
P39748 Flap endonuclease 1 Enzyme C00004694 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00004694 2 / 0
P14618 Pyruvate kinase PKM Enzyme C00001096 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001096 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00003393 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00004694 1 / 1
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00001096 0 / 0
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00004694 2 / 2
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003393 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00001096 4 / 3
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003393 0 / 0
P00747 Plasminogen S1A C00003865 1 / 2
Q13748 Tubulin alpha-3C/D chain Structural C00004694 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004694 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004694 1 / 0
P04350 Tubulin beta-4A chain Structural C00004694 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004694 0 / 0
P07437 Tubulin beta chain Structural C00004694 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004694 1 / 1
P68371 Tubulin beta-4B chain Structural C00004694 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004694 2 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00004694 0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein C00004694 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004694 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004694 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004694 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004694 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00004694 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (34)

OMIM preferred title UniProt
#300018 46,xy sex reversal 2; srxy2 P51843
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300200 Adrenal hypoplasia, congenital; ahc P51843
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114500 Colorectal cancer; crc P84022
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#133239 Esophageal cancer P04637
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#611603 Lissencephaly 3; lis3 Q71U36
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#260500 Papilloma of choroid plexus; cpp P04637
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#217090 Plasminogen deficiency, type i P00747
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (52)

KEGG name UniProt
H00223 Inherited thrombophilia P00747 (related)
H01206 Plasminogen deficiency P00747 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00192 Xanthinuria P47989 (related)
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)