Grindelia squarrosa

• Index
• Plant Species
• Natural Activity
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Grindelia squarrosa
Genus	Grindelia
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Grindelia squarrosa
Linked NCBI taxonomy ID	1114761
Linked level	species

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Natural Activity

List (13)

Species	Activity
Grindelia squarrosa (Pursh) Dunal	Abortifacient
Grindelia squarrosa (Pursh) Dunal	Antibacterial
Grindelia squarrosa (Pursh) Dunal	Antidote
Grindelia squarrosa (Pursh) Dunal	Antiedemic
Grindelia squarrosa (Pursh) Dunal	Antiinflammatory
Grindelia squarrosa (Pursh) Dunal	Antiseptic
Grindelia squarrosa (Pursh) Dunal	Antispasmodic
Grindelia squarrosa (Pursh) Dunal	Antitussive
Grindelia squarrosa (Pursh) Dunal	Contraceptive
Grindelia squarrosa (Pursh) Dunal	Expectorant
Grindelia squarrosa (Pursh) Dunal	Fungicide
Grindelia squarrosa (Pursh) Dunal	Sedative
Grindelia squarrosa (Pursh) Dunal	Stimulant

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001096	Santin	CHEMBL161957	C104803	9 / 7 / 5		No. 3	No. 15
C00004596	6-Methoxykaempferol 3-methyl ether / 5,7,4'-Trihydroxy-3,6-dimethoxyflavone / 5,7-Dihydroxy-2-(4-hydroxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one	CHEMBL351607	C014868			No. 3	No. 15
C00004646	Pachypodol / Quercetin 3,3',7-trimethyl ether / 5,4'-Dihydroxy-3,7,3'-trimethoxyflavone / 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL165180	C008751	1 / 2 / 0		No. 3	No. 15
C00004647	Ayanin / 3,7,4'-Tri-O-methylquercetin / 5,3'-Dihydroxy-3,7,4'-trimethoxyflavone / 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one	CHEMBL74898		18 / 10 / 2		No. 3	No. 15

Human Protein / Gene in interactions

27 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UNQ0	ATP-binding cassette sub-family G member 2	ATP binding cassette	C00004646 C00004647	2 / 0
P68366	Tubulin alpha-4A chain	Structural	C00004647	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001096	1 / 1
P14618	Pyruvate kinase PKM	Enzyme	C00001096	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00001096	1 / 1
P08183	Multidrug resistance protein 1	drug	C00004647	1 / 0
O75496	Geminin	Unclassified protein	C00001096	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001096	0 / 0
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00001096	0 / 0
P33527	Multidrug resistance-associated protein 1	drugs	C00004647	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001096	4 / 3
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001096	1 / 0
Q13748	Tubulin alpha-3C/D chain	Structural	C00004647	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00001096	0 / 0
Q9H4B7	Tubulin beta-1 chain	Structural	C00004647	1 / 0
P04350	Tubulin beta-4A chain	Structural	C00004647	2 / 0
Q3ZCM7	Tubulin beta-8 chain	Structural	C00004647	0 / 0
P07437	Tubulin beta chain	Structural	C00004647	0 / 0
Q71U36	Tubulin alpha-1A chain	Structural	C00004647	1 / 1
P68371	Tubulin beta-4B chain	Structural	C00004647	0 / 0
Q13509	Tubulin beta-3 chain	Structural	C00004647	2 / 1
P68363	Tubulin alpha-1B chain	Unclassified protein	C00004647	0 / 0
Q13885	Tubulin beta-2A chain	Structural	C00004647	0 / 0
Q6PEY2	Tubulin alpha-3E chain	Unclassified protein	C00004647	0 / 0
Q9BQE3	Tubulin alpha-1C chain	Unclassified protein	C00004647	0 / 0
Q9BUF5	Tubulin beta-6 chain	Structural	C00004647	0 / 0
Q9BVA1	Tubulin beta-2B chain	Structural	C00004647	1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions