Species

KNApSAcK Entry

Organism name Artemisia mesatlantica
Genus Artemisia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Artemisia mesatlantica
Linked NCBI taxonomy ID 1287615
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001105 External link 512 Tangeretin
/ 4',5,6,7,8-Pentamethoxyflavone
CHEMBL73930
C059006
12 / 11 / 11 2 / 0 No. 8 No. 15
C00003946 External link 512 5,4'-Dihidroxy-6,7,3',5'-tetramethoxyflavone
/ 5-Hydroxy-2-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
CHEMBL1524286
16 / 10 / 6 No. 8 No. 15

Human Protein / Gene in interactions

28 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00001105 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003946 1 / 1
P06746 DNA polymerase beta Enzyme C00003946 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00003946 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001105 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00001105 3 / 1
P08183 Multidrug resistance protein 1 drug C00001105 1 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00003946 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001105 0 / 0
P50281 Matrix metalloproteinase-14 M10A C00003946 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00003946 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00001105 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001105 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001105 2 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003946 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001105 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003946 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00003946 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003946 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00003946 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00003946 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003946 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003946 1 / 0
O00255 Menin Unclassified protein C00001105 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001105 1 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00003946 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00003946 2 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001105 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001105
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001105

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614490 Blood group, junior system; jr Q9UNQ0
#114500 Colorectal cancer; crc Q14191
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612244 Inflammatory bowel disease 13; ibd13 P08183
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#277700 Werner syndrome; wrn Q14191
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)