Species

KNApSAcK Entry

Organism name Mandarina satsuma
Genus Mandarina
Family Camaenidae
Kingdom Animalia

NCBI taxonomy

Entry

Linked NCBI taxonomy name Mandarina
Linked NCBI taxonomy ID 83227
Linked level genus

Family

Family in NCBI taxonomy Bradybaenidae
ID 89998

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001105 External link 512 Tangeretin
/ 4',5,6,7,8-Pentamethoxyflavone
CHEMBL73930
C059006
12 / 11 / 11 2 / 0 No. 8 No. 15
C00003912 External link 512 Isosinensetin
/ 6-Demethoxynobiletin
/ 5,7,8,3',4'-Pentamethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL451707
No. 8 No. 15

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O94956 Solute carrier organic anion transporter family member 2B1 Unclassified protein C00001105 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00001105 1 / 1
P10828 Thyroid hormone receptor beta NR1A2 C00001105 3 / 1
P08183 Multidrug resistance protein 1 drug C00001105 1 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001105 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00001105 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001105 0 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00001105 2 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001105 0 / 1
O00255 Menin Unclassified protein C00001105 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001105 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001105 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00001105
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00001105

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614490 Blood group, junior system; jr Q9UNQ0
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612244 Inflammatory bowel disease 13; ibd13 P08183
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989

KEGG DISEASE (11)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00192 Xanthinuria P47989 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)