Larix spp.
Species
KNApSAcK Entry
| Organism name | Larix spp. |
|---|---|
| Genus | Larix |
| Family | Pinaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Larix |
|---|---|
| Linked NCBI taxonomy ID | 3325 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Pinaceae |
|---|---|
| ID | 3318 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Spermatophyta |
|---|---|
| ID | 58024 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004763
|
Laricitrin
|
No. 3 | No. 15 |
|
||||
|
C00001110
|
Vitexin
/ Apigenin 8-C-glucoside / 8-D-Glucosyl-4',5,7-trihydroxyflavone / 8-beta-D-Glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL487417
CHEMBL1332209 CHEMBL1357921 |
16 / 4 / 8 | No. 22 | No. 15 |
|
||
|
C00002727
|
Coniferin
/ Coniferoside |
CHEMBL459056
|
C016316
|
2 / 0 / 0 | No. 678 | No. 6 |
|
Human Protein / Gene in interactions
18 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001110 | 1 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001110 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001110 | 0 / 1 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00002727 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00002727 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001110 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00001110 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001110 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001110 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001110 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001110 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001110 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00001110 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001110 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001110 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001110 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001110 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001110 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (4)
| OMIM | preferred title | UniProt |
|---|---|---|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|