Panax quinquefolium
Species
KNApSAcK Entry
| Organism name | Panax quinquefolium |
|---|---|
| Genus | Panax |
| Family | Araliaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Panax quinquefolius |
|---|---|
| Linked NCBI taxonomy ID | 44588 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Araliaceae |
|---|---|
| ID | 4050 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (9)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00030399
|
Panaxoside Rg2
/ Ginsenoside Rg2 |
CHEMBL505747
CHEMBL1095005 CHEMBL1095006 CHEMBL1475728 |
C026474
|
5 / 0 / 0 | 7 / 2 | No. 32 | No. 51 |
|
|
C00029310
|
Ginsenoside F4
/ (20E)-Ginsenoside F4 / (-)-(20E)-Ginsenoside F4 |
No. 32 | No. 51 |
|
||||
|
C00030401
|
Ginsenoside Rg8
/ (+)-Ginsenoside Rg8 |
No. 32 | No. 51 |
|
||||
|
C00029311
|
(20R)-Ginsenoside RH1
|
CHEMBL466844
|
No. 99 |
|
||||
|
C00030402
|
Ginsenoside Rh1
|
CHEMBL466844
|
C425564
|
8 / 0 | No. 99 |
|
||
|
C00030388
|
Ginsenoside F1
|
CHEMBL584011
|
C055327
|
No. 99 |
|
|||
|
C00001284
|
Panaxynol
/ Falcarinol / (-)-Falcarinol |
CHEMBL71260
CHEMBL368712 |
C018541
|
0 / 2 | No. 940 | No. 69 |
|
|
|
C00031489
|
1,8-Heptadecadiene-4,6-diyne-3,10-diol
|
CHEMBL463807
CHEMBL448210 |
C056818
|
No. 940 | No. 69 |
|
||
|
C00030922
|
Panaxydol
/ (-)-Panaxydol |
C055778
|
6 / 1 | No. 3682 |
|
Human Protein / Gene in interactions
5 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P11387 | DNA topoisomerase 1 | Isomerase | C00030399 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00030399 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00030399 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00030399 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00030399 | 0 / 0 |
21 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 200186 | CRTC2, TORC-2, TORC2 | CREB regulated transcription coactivator 2 |
C00030399
|
| 92579 | G6PC3, SCN4, UGRP | glucose 6 phosphatase, catalytic, 3 (EC:3.1.3.9) |
C00030399
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00030399
|
| 8431 | NR0B2, SHP, SHP1 | nuclear receptor subfamily 0, group B, member 2 |
C00030399
|
| 5105 | PCK1, PEPCK-C, PEPCK1, PEPCKC | phosphoenolpyruvate carboxykinase 1 (soluble) (EC:4.1.1.32) |
C00030399
|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00030399
|
| 6794 | STK11, LKB1, PJS, hLKB1 | serine/threonine kinase 11 (EC:2.7.11.1) |
C00030399
|
| 174 | AFP, FETA, HPAFP | alpha-fetoprotein |
C00030922
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00030922
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00030922
|
| 3397 | ID1, ID, bHLHb24 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
C00030922
|
| 3398 | ID2, GIG8, ID2A, ID2H, bHLHb26 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
C00030922
|
| 5925 | RB1, OSRC, RB, p105-Rb, pRb, pp110 | retinoblastoma 1 |
C00030922
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00030402
|
| 3676 | ITGA4, CD49D, IA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
C00030402
|
| 3683 | ITGAL, CD11A, LFA-1, LFA1A | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
C00030402
|
| 3688 | ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
C00030402
|
| 3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00030402
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00030402
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00030402
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00030402
|