Quisqualis indica
Species
KNApSAcK Entry
| Organism name | Quisqualis indica |
|---|---|
| Genus | Quisqualis |
| Family | Combretaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Combretum indicum |
|---|---|
| Linked NCBI taxonomy ID | 3956 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Combretaceae |
|---|---|
| ID | 3954 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00001391
|
Quisqualic acid
|
CHEMBL279956
CHEMBL168279 |
D016318
|
31 / 11 / 14 | 1 / 3 | No. 6504 |
|
Human Protein / Gene in interactions
31 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001391 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001391 | 2 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001391 | 0 / 1 |
| Q14831 | Metabotropic glutamate receptor 7 | Metabotropic glutamate receptor | C00001391 | 0 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00001391 | 1 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001391 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001391 | 0 / 0 |
| Q14416 | Metabotropic glutamate receptor 2 | Metabotropic glutamate receptor | C00001391 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00001391 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001391 | 0 / 0 |
| O15303 | Metabotropic glutamate receptor 6 | Metabotropic glutamate receptor | C00001391 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001391 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001391 | 0 / 0 |
| Q04609 | Glutamate carboxypeptidase 2 | M28B | C00001391 | 0 / 0 |
| Q14833 | Metabotropic glutamate receptor 4 | Metabotropic glutamate receptor | C00001391 | 0 / 0 |
| Q13255 | Metabotropic glutamate receptor 1 | Metabotropic glutamate receptor | C00001391 | 1 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001391 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001391 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001391 | 0 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001391 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001391 | 0 / 0 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001391 | 0 / 0 |
| Q9UPY5 | Cystine/glutamate transporter | Unclassified protein | C00001391 | 0 / 0 |
| Q14832 | Metabotropic glutamate receptor 3 | Metabotropic glutamate receptor | C00001391 | 0 / 0 |
| P41594 | Metabotropic glutamate receptor 5 | Metabotropic glutamate receptor | C00001391 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001391 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001391 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001391 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001391 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00001391 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001391 | 1 / 2 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 2915 | GRM5, GPRC1E, MGLUR5, mGlu5 | glutamate receptor, metabotropic 5 |
C00001391
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (11)
| OMIM | preferred title | UniProt |
|---|---|---|
| #210900 | Bloom syndrome; blm |
P54132
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #257270 | Night blindness, congenital stationary, type 1b; csnb1b |
O15303
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #614831 | Spinocerebellar ataxia, autosomal recessive 13; scar13 |
Q13255
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00787 | Congenital stationary night blindness (CSNB) |
O15303
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|